RT Journal Article T1 Complicated intra-abdominal infections in Europe: a comprehensive review of the CIAO study. A1 Sartelli, Massimo A1 Catena, Fausto A1 Ansaloni, Luca A1 Leppaniemi, Ari A1 Taviloglu, Korhan A1 van Goor, Harry A1 Viale, Pierluigi A1 Lazzareschi, Daniel Vasco A1 Coccolini, Federico A1 Corbella, Davide A1 de Werra, Carlo A1 Marrelli, Daniele A1 Colizza, Sergio A1 Scibè, Rodolfo A1 Alis, Halil A1 Torer, Nurkan A1 Navarro, Salvador A1 Sakakushev, Boris A1 Massalou, Damien A1 Augustin, Goran A1 Catani, Marco A1 Kauhanen, Saila A1 Pletinckx, Pieter A1 Kenig, Jakub A1 Di Saverio, Salomone A1 Jovine, Elio A1 Guercioni, Gianluca A1 Skrovina, Matej A1 Díaz-Nieto, Rafael A1 Ferrero, Alessandro A1 Rausei, Stefano A1 Laine, Samipetteri A1 Major, Piotr A1 Angst, Eliane A1 Pittet, Olivier A1 Herych, Ihor A1 Agresta, Ferdinando A1 Vettoretto, Nereo A1 Poiasina, Elia A1 Tepp, Jaan A1 Weiss, Gunter A1 Vasquez, Giorgio A1 Vladov, Nikola A1 Tranà, Cristian A1 Delibegovic, Samir A1 Dziki, Adam A1 Giraudo, Giorgio A1 Pereira, Jorge A1 Tzerbinis, Helen A1 van Dellen, David A1 Hutan, Martin A1 Vereczkei, Andras A1 Krasniqi, Avdyl A1 Seretis, Charalampos A1 Mesina, Cristian A1 Rems, Miran A1 Campanile, Fabio Cesare A1 Coletta, Pietro A1 Uotila-Nieminen, Mirjami A1 Dente, Mario A1 Bouliaris, Konstantinos A1 Lasithiotakis, Konstantinos A1 Khokha, Vladimir A1 Zivanovic, Dragoljub A1 Smirnov, Dmitry A1 Marinis, Athanasios A1 Negoi, Ionut A1 Ney, Ludwig A1 Bini, Roberto A1 León, Miguel A1 Aloia, Sergio A1 Huchon, Cyrille A1 Moldovanu, Radu A1 de Melo, Renato Bessa A1 Giakoustidis, Dimitrios A1 Ioannidis, Orestis A1 Cucchi, Michele A1 Pintar, Tadeja A1 Krivokapic, Zoran A1 Petrovic, Jelena K1 Infecciones Intraabdominales K1 Estudio Multicéntrico K1 Abceso Abdominal K1 Enfermedad Crítica K1 Humanos K1 Procedimientos Quirúrgicos del Sistema Digestivo K1 Farmacoresistencia Microbiana K1 Reoperación K1 Infección Hospitalaria K1 Adulto AB The CIAO Study ("Complicated Intra-Abdominal infection Observational" Study) is a multicenter investigation performed in 68 medical institutions throughout Europe over the course of a 6-month observational period (January-June 2012).Patients with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study.2,152 patients with a mean age of 53.8 years (range: 4-98 years) were enrolled in the study. 46.3% of the patients were women and 53.7% were men. Intraperitoneal specimens were collected from 62.2% of the enrolled patients, and from these samples, a variety of microorganisms were collectively identified.The overall mortality rate was 7.5% (163/2.152).According to multivariate analysis of the compiled data, several criteria were found to be independent variables predictive of patient mortality, including patient age, the presence of an intestinal non-appendicular source of infection (colonic non-diverticular perforation, complicated diverticulitis, small bowel perforation), a delayed initial intervention (a delay exceeding 24 hours), sepsis and septic shock in the immediate post-operative period, and ICU admission.Given the sweeping geographical distribution of the participating medical centers, the CIAO Study gives an accurate description of the epidemiological, clinical, microbiological, and treatment profiles of complicated intra-abdominal infections (IAIs) throughout Europe. PB BioMed Central YR 2012 FD 2012-11-29 LK http://hdl.handle.net/10668/1112 UL http://hdl.handle.net/10668/1112 LA en NO Sartelli M, Catena F, Ansaloni L, Leppaniemi A, Taviloglu K, van Goor H, et al. Complicated intra-abdominal infections in Europe: a comprehensive review of the CIAO study. World J Emerg Surg. 2012; 7(1):36 NO Journal Article; DS RISalud RD Apr 8, 2025