TY  - JOUR
AU  - Gabasa, Marta
AU  - Radisky, Evette S
AU  - Ikemori, Rafael
AU  - Bertolini, Giulia
AU  - Arshakyan, Marselina
AU  - Hockla, Alexandra
AU  - Duch, Paula
AU  - Rondinone, Ornella
AU  - Llorente, Alejandro
AU  - Maqueda, Maria
AU  - Davalos, Albert
AU  - Gavilán, Elena
AU  - Perera, Alexandre
AU  - Ramírez, Josep
AU  - Gascón, Pere
AU  - Reguart, Noemí
AU  - Roz, Luca
AU  - Radisky, Derek C
AU  - Alcaraz, Jordi
PY  - 2021
DO  - 10.1016/j.canlet.2021.01.028
UR  - http://hdl.handle.net/10668/17329
T2  - Cancer letters
AB  - Large cell carcinoma (LCC) is a rare and aggressive lung cancer subtype with poor prognosis and no targeted therapies. Tumor-associated fibroblasts (TAFs) derived from LCC tumors exhibit premature senescence, and coculture of pulmonary fibroblasts...
LA  - en
KW  - Cancer-associated fibroblasts
KW  - MMP1
KW  - TGF-β
KW  - lung cancer
KW  - senescence
KW  - Animals
KW  - Cancer-Associated Fibroblasts
KW  - Carcinoma, Large Cell
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cellular Senescence
KW  - Coculture Techniques
KW  - Disease Progression
KW  - Female
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Lung Neoplasms
KW  - Matrix Metalloproteinase 1
KW  - Mice, Nude
KW  - Oxidative Stress
KW  - Paracrine Communication
KW  - Receptor, PAR-1
KW  - Signal Transduction
KW  - Transforming Growth Factor beta1
KW  - Tumor Burden
TI  - MMP1 drives tumor progression in large cell carcinoma of the lung through fibroblast senescence.
TY  - research article
VL  - 507
ER  -