%0 Journal Article
%A Zavala-Crichton, Juan Pablo
%A Esteban-Cornejo, Irene
%A Solis-Urra, Patricio
%A Mora-Gonzalez, José
%A Cadenas-Sanchez, Cristina
%A Rodriguez-Ayllon, María
%A Migueles, Jairo H.
%A Molina-Garcia, Pablo
%A Verdejo-Roman, Juan
%A Kramer, Arthur F.
%A Hillman, Charles H.
%A Erickson, Kirk I.
%A Catena, Andrés
%A Ortega, Francisco B.
%T Association of Sedentary Behavior with Brain Structure and Intelligence in Children with Overweight or Obesity: The ActiveBrains Project
%D 2020
%U http://hdl.handle.net/10668/4124
%X We investigated the associations of di_erent sedentary behaviors (SB) with gray matter volume and we tested whether SB related to gray matter volume is associated with intelligence. Methods: 99 children with overweight or obesity aged 8–11 years participated in this cross-sectional study. SB was measured using the Youth Activity Profile-Spain questionnaire. T1-weighted images were acquired with a 3.0 T Magnetom Tim Trio system. Intelligence was assessed with the Kaufman Brief Test. Whole-brain voxel-wise multiple regression models were used to test the associations of each SB with gray matter volume. Results: Watching TV was associated with lower gray matter volume in six brain regions (_ ranging 􀀀0.314 to 􀀀0.489 and cluster size 106 to 323 voxels; p < 0.001), playing video games in three brain regions (_ ranging 􀀀0.391 to 􀀀0.359, and cluster size 96 to 461 voxels; p < 0.001) and total sedentary time in two brain regions (_ ranging 􀀀0.341 to 􀀀0.352, and cluster size 897 to 2455 voxels; p < 0.001). No brain regions showed a significant positive association (all p > 0.05). Two brain regions were related, or borderline related, to intelligence. Conclusions: SB could have the potential to negatively influence brain structure and, in turn, intelligence in children with overweight/obesity.
%K Sedentariness
%K TV viewing
%K Magnetic resonance imaging
%K Brain
%K Cognition
%K Childhood
%K Obesity
%K Sedentary behavior
%K Imagen por resonancia magnética
%K Encéfalo
%K Cognición
%K Obesidad
%K Conducta sedentaria
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