TY  - JOUR
AU  - García-Pichardo, Desiré
AU  - Cañas, Juan C
AU  - García-Rubio, María L
AU  - Gómez-González, Belén
AU  - Rondón, Ana G
AU  - Aguilera, Andrés
PY  - 2017
DO  - 10.1016/j.molcel.2017.05.014
UR  - http://hdl.handle.net/10668/11265
T2  - Molecular cell
AB  - R loops have positive physiological roles, but they can also be deleterious by causing genome instability, and the mechanisms for this are unknown. Here we identified yeast histone H3 and H4 mutations that facilitate R loops but do not cause...
LA  - en
KW  - H3 serine-10 phosphorylation
KW  - R loops
KW  - RNA-DNA hybrids
KW  - chromatin
KW  - chromatin compaction
KW  - chromosome fragility
KW  - genome instability
KW  - histones H3 and H4
KW  - Chromatin
KW  - Chromatin Assembly and Disassembly
KW  - DNA Damage
KW  - DNA Helicases
KW  - DNA, Fungal
KW  - Genome, Fungal
KW  - Genomic Instability
KW  - Histones
KW  - Nuclear Proteins
KW  - Nucleic Acid Conformation
KW  - Phosphorylation
KW  - Point Mutation
KW  - Protein Conformation
KW  - Protein Processing, Post-Translational
KW  - RNA Helicases
KW  - RNA, Fungal
KW  - Saccharomyces cerevisiae
KW  - Saccharomyces cerevisiae Proteins
KW  - Structure-Activity Relationship
TI  - Histone Mutants Separate R Loop Formation from Genome Instability Induction.
TY  - research article
VL  - 66
ER  -