TY  - JOUR
AU  - Kerick, Martin
AU  - Acosta-Herrera, Marialbert
AU  - Simeón-Aznar, Carmen Pilar
AU  - Callejas, José Luis
AU  - Assassi, Shervin
AU  - International SSc Group
AU  - Proudman, Susanna M
AU  - Nikpour, Mandana
AU  - Australian Scleroderma Interest Group (ASIG)
AU  - PRECISESADS Clinical Consortium
AU  - Hunzelmann, Nicolas
AU  - Moroncini, Gianluca
AU  - de Vries-Bouwstra, Jeska K
AU  - Orozco, Gisela
AU  - Barton, Anne
AU  - Herrick, Ariane L
AU  - Terao, Chikashi
AU  - Allanore, Yannick
AU  - Fonseca, Carmen
AU  - Alarcón-Riquelme, Marta Eugenia
AU  - Radstake, Timothy R D J
AU  - Beretta, Lorenzo
AU  - Denton, Christopher P
AU  - Mayes, Maureen D
AU  - Martin, Javier
PY  - 2022
DO  - 10.1038/s41525-022-00327-8
UR  - http://hdl.handle.net/10668/19554
T2  - NPJ genomic medicine
AB  - Copy number (CN) polymorphisms of complement C4 play distinct roles in many conditions, including immune-mediated diseases. We investigated the association of C4 CN with systemic sclerosis (SSc) risk. Imputed total C4, C4A, C4B, and HERV-K CN were...
LA  - en
TI  - Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis.
TY  - research article
VL  - 7
ER  -