TY - JOUR AU - Weiss, Sarah A AU - Sznol, Mario AU - Shaheen, Montaser AU - Berciano-Guerrero, Miguel-Angel AU - Muñoz-Couselo, Eva AU - Rodriguez-Abreu, Delvys AU - Boni, Valentina AU - Schuchter, Lynn M AU - Gonzalez-Cao, Maria AU - Arance, Ana AU - Wei, Wei AU - Ganti, Apar Kishor AU - Hauke, Ralph J AU - Berrocal, Alfonso AU - Iannotti, Nicholas O AU - Hsu, Frank J AU - Kluger, Harriet M PY - 2023 DO - 10.1158/1078-0432.CCR-23-0475 SN - 1557-3265 UR - https://hdl.handle.net/10668/28504 T2 - Clinical Cancer Research AB - Purpose: Disease progression during or after anti-PD-1-based treatment is common in advanced melanoma. Sotigalimab is a CD40 agonist antibody with a unique epitope specificity and Fc receptor binding profile optimized for activation of CD40-expressing... LA - en PB - American Association for Cancer Research KW - Nivolumab KW - Melanoma KW - Sotigalimab KW - Immune Checkpoint Inhibitors KW - Asthenia KW - Myalgia KW - Fatigue KW - Disease Progression KW - Nausea KW - Headache TI - A Phase II Trial of the CD40 Agonistic Antibody Sotigalimab (APX005M) in Combination with Nivolumab in Subjects with Metastatic Melanoma with Confirmed Disease Progression on Anti-PD-1 Therapy. TY - research article VL - 30 ER -