TY  - JOUR
AU  - Pastushenko, Ievgenia
AU  - Mauri, Federico
AU  - Song, Yura
AU  - de Cock, Florian
AU  - Meeusen, Bob
AU  - Swedlund, Benjamin
AU  - Impens, Francis
AU  - Van Haver, Delphi
AU  - Opitz, Matthieu
AU  - Thery, Manuel
AU  - Bareche, Yacine
AU  - Lapouge, Gaelle
AU  - Vermeersch, Marjorie
AU  - Van Eycke, Yves-Rémi
AU  - Balsat, Cédric
AU  - Decaestecker, Christine
AU  - Sokolow, Youri
AU  - Hassid, Sergio
AU  - Perez-Bustillo, Alicia
AU  - Agreda-Moreno, Beatriz
AU  - Rios-Buceta, Luis
AU  - Jaen, Pedro
AU  - Redondo, Pedro
AU  - Sieira-Gil, Ramon
AU  - Millan-Cayetano, Jose F
AU  - Sanmatrtin, Onofre
AU  - D'Haene, Nicky
AU  - Moers, Virginie
AU  - Rozzi, Milena
AU  - Blondeau, Jeremy
AU  - Lemaire, Sophie
AU  - Scozzaro, Samuel
AU  - Janssens, Veerle
AU  - De Troya, Magdalena
AU  - Dubois, Christine
AU  - Pérez-Morga, David
AU  - Salmon, Isabelle
AU  - Sotiriou, Christos
AU  - Helmbacher, Francoise
AU  - Blanpain, Cédric
PY  - 2020
DO  - 10.1038/s41586-020-03046-1
UR  - https://hdl.handle.net/10668/26673
T2  - Nature
AB  - FAT1, which encodes a protocadherin, is one of the most frequently mutated genes in human cancers1-5. However, the role and the molecular mechanisms by which FAT1 mutations control tumour initiation and progression are poorly understood. Here, using...
LA  - en
KW  - Adaptor Proteins, Signal Transducing
KW  - Animals
KW  - Cadherins
KW  - Carcinoma, Squamous Cell
KW  - Disease Progression
KW  - Enhancer of Zeste Homolog 2 Protein
KW  - Epithelial Cells
KW  - Epithelial-Mesenchymal Transition
KW  - Gene Deletion
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Hyaluronan Receptors
KW  - Lung Neoplasms
KW  - Mesoderm
KW  - Mice
KW  - Neoplasm Metastasis
KW  - Neoplasms
KW  - Neoplastic Stem Cells
KW  - Phenotype
KW  - Phosphoproteins
KW  - Proteomics
KW  - SOXB1 Transcription Factors
KW  - Signal Transduction
KW  - Skin Neoplasms
KW  - Transcription Factors
KW  - YAP-Signaling Proteins
KW  - Zinc Finger E-box-Binding Homeobox 1
KW  - src-Family Kinases
TI  - Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
TY  - research article
VL  - 589
ER  -