RT Generic
T1 Childhood maltreatment and social functioning in psychotic disorders: a systematic review protocol
A1 Fares-Otero, Natalia E.
A1 Pfaltz, Monique C.
A1 Rodriguez-Jimenez, Roberto
A1 Schaefer, Ingo
A1 Trautmann, Sebastian
K1 child abuse
K1 neglect
K1 social cognitive skills
K1 interpersonal relationships
K1 community functioning
K1 psychosis
K1 systematic review
K1 Posttraumatic-stress-disorder
K1 Trauma-focused treatment
K1 1st-episode psychosis
K1 Schizophrenia spectrum
K1 Mental-disorders
K1 Physical abuse
K1 Experiences
K1 Adversity
K1 Impact
K1 Individuals
AB Background Childhood maltreatment (CM) is thought to play a key role in the etiology and course of psychotic disorders (PD). In addition, CM is related to neurobiological and clinical characteristics that can lead to poor social functioning. However, the extent to which CM and social functioning are directly associated in individuals with PD, is unclear. Therefore, we aim to systematically review the literature to provide an estimate on the strength of the association between CM and different domains of social functioning in PD and to summarize potential moderators and mediators of this association. Methods and analysis To identify relevant studies, we will systematically search the following databases: Pubmed (Medline), PsycInfo, Embase, Web of Science (Core Collection), and Pilots (trauma), manually search reference lists and contact experts in the field. Studies will be included if they investigate and report on the association between CM (exposure) and social functioning (outcome) in adults with PD. Two independent reviewers will screen titles, abstracts and full texts according to eligibility criteria, perform data extraction and assess study quality according to a modified version of the Newcastle-Ottawa Scale. Analysis Effect estimates will be pooled in a meta-analysis. Heterogeneity and publication bias will be assessed and the effects of potential moderators (genetic factors, type of diagnosis, duration of illness, type of CM and age at the time of CM exposure) will be analyzed using meta-regressions. Candidate moderators and mediators (neurocognition, cognitive schemas, comorbidities, stress sensitivity, attachment) will be also examined qualitatively. Ethics and dissemination Because this review will make use of already published data, ethical approval will not be sought. This work has the potential to inform upcoming investigations on the association between the exposure to CM in PD and social functioning. PROSPERO registration number CRD42020175244.
PB Taylor & francis ltd
SN 2000-8198
YR 2021
FD 2021-01-01
LK https://hdl.handle.net/10668/25392
UL https://hdl.handle.net/10668/25392
LA en
DS RISalud
RD Apr 17, 2025