RT Journal Article
T1 The prevalence of left and right bundle branch block morphology ventricular tachycardia amongst patients with arrhythmogenic cardiomyopathy and sustained ventricular tachycardia: insights from the European Survey on Arrhythmogenic Cardiomyopathy.
A1 Belhassen, Bernard
A1 Laredo, Mikael
A1 Roudijk, Rob W
A1 Peretto, Giovanni
A1 Zahavi, Guy
A1 Sen-Chowdhry, Srijita
A1 Badenco, Nicolas
A1 Te Riele, Anneline S J M
A1 Sala, Simone
A1 Duthoit, Guillaume
A1 van Tintelen, J Peter
A1 Paglino, Gabriele
A1 Sellal, Jean-Marc
A1 Gasperetti, Alessio
A1 Arbelo, Elena
A1 Andorin, Antoine
A1 Ninni, Sandro
A1 Rollin, Anne
A1 Peichl, Petr
A1 Waintraub, Xavier
A1 Bosman, Laurens P
A1 Pierre, Bertrand
A1 Nof, Eyal
A1 Miles, Chris
A1 Tfelt-Hansen, Jacob
A1 Protonotarios, Alexandros
A1 Giustetto, Carla
A1 Sacher, Frederic
A1 Hermida, Jean-Sylvain
A1 Havranek, Stepan
A1 Calo, Leonardo
A1 Casado-Arroyo, Ruben
A1 Conte, Giulio
A1 Letsas, Konstantinos P
A1 Zorio, Esther
A1 Bermúdez-Jiménez, Francisco J
A1 Behr, Elijah R
A1 Beinart, Roy
A1 Fauchier, Laurent
A1 Kautzner, Josef
A1 Maury, Philippe
A1 Lacroix, Dominique
A1 Probst, Vincent
A1 Brugada, Josep
A1 Duru, Firat
A1 de Chillou, Christian
A1 Bella, Paolo Della
A1 Gandjbakhch, Estelle
A1 Hauer, Richard
A1 Milman, Anat
K1 Arrhythmogenic cardiomyopathy
K1 Arrhythmogenic left ventricular cardiomyopathy
K1 Arrhythmogenic right ventricular cardiomyopathy/dysplasia
K1 European survey
K1 Genetics
K1 Ventricular tachycardia
AB In arrhythmogenic cardiomyopathy (ACM), sustained ventricular tachycardia (VT) typically displays a left bundle branch block (LBBB) morphology while a right bundle branch block (RBBB) morphology is rare. The present study assesses the VT morphology in ACM patients with sustained VT and their clinical and genetic characteristics. Twenty-six centres from 11 European countries provided information on 954 ACM patients who had ≥1 episode of sustained VT spontaneously documented during patients' clinical course. Arrhythmogenic cardiomyopathy was defined according to the 2010 Task Force Criteria, and VT morphology according to the QRS pattern in V1. Overall, 882 (92.5%) patients displayed LBBB-VT alone and 72 (7.5%) RBBB-VT [alone in 42 (4.4%) or in combination with LBBB-VT in 30 (3.1%)]. Male sex prevalence was 79.3%, 88.1%, and 56.7% in the LBBB-VT, RBBB-VT, and LBBB + RBBB-VT groups, respectively (P = 0.007). First RBBB-VT occurred 5 years after the first LBBB-VT (46.5 ± 14.4 vs 41.1 ± 15.8 years, P = 0.011). An implanted cardioverter-defibrillator was more frequently implanted in the RBBB-VT (92.9%) and the LBBB + RBBB-VT groups (90%) than in the LBBB-VT group (68.1%) (P  RBBB-VT accounts for a significant proportion of sustained VTs in ACM. Sex and type of pathogenic mutations were associated with VT type, female sex with LBBB + RBBB-VT, and DSP mutation with RBBB-VT.
YR 2022
FD 2022
LK http://hdl.handle.net/10668/19774
UL http://hdl.handle.net/10668/19774
LA en
DS RISalud
RD Apr 8, 2025