TY - JOUR AU - Maldonado-Perez, Noelia AU - Tristan-Manzano, Maria AU - Justicia-Lirio, Pedro AU - Martinez-Planes, Elena AU - Muñoz, Pilar AU - Pavlovic, Kristina AU - Cortijo-Gutierrez, Marina AU - Blanco-Benitez, Carlos AU - Castella, Maria AU - Juan, Manel AU - Wenes, Mathias AU - Romero, Pedro AU - Molina-Estevez, Francisco J AU - Marañon, Concepcion AU - Herrera, Concha AU - Benabdellah, Karim AU - Martin, Francisco PY - 2022 DO - 10.3389/fimmu.2022.1011858 UR - http://hdl.handle.net/10668/20594 T2 - Frontiers in immunology AB - Autologous T cells expressing the Chimeric Antigen Receptor (CAR) have been approved as advanced therapy medicinal products (ATMPs) against several hematological malignancies. However, the generation of patient-specific CAR-T products delays treatment... LA - en PB - Frontiers Research Foundation KW - CAR-T cells KW - CRISPR/Cas9 KW - TCRKO KW - Large deletions KW - Lymphoma KW - Off-the-shelf KW - Safety KW - Humans KW - Receptors, Chimeric Antigen KW - Immunotherapy, Adoptive KW - T-Lymphocytes KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma KW - Lymphoma, B-Cell TI - Efficacy and safety of universal (TCRKO) ARI-0001 CAR-T cells for the treatment of B-cell lymphoma. TY - research article VL - 13 ER -