RT Journal Article T1 SEOM clinical guideline for treatment of kidney cancer (2017). A1 Gallardo, E A1 Mendez-Vidal, M J A1 Perez-Gracia, J L A1 Sepulveda-Sanchez, J M A1 Campayo, M A1 Chirivella-Gonzalez, I A1 Garcia-Del-Muro, X A1 Gonzalez-Del-Alba, A A1 Grande, E A1 Suarez, C K1 Kidney cancer K1 Molecular pathology K1 Systemic therapy AB The goal of this article is to provide recommendations about the management of kidney cancer. Based on pathologic and molecular features, several kidney cancer variants were described. Nephron-sparing techniques are the gold standard of localized disease. After a randomized trial, sunitinib could be considered in adjuvant treatment in high-risk patients. Patients with advanced disease constitute a heterogeneous population. Prognostic classification should be considered. Both sunitinib and pazopanib are the standard options for first-line systemic therapy in advanced renal cell carcinoma. Based on the results of two randomized trials, both nivolumab and cabozantinib should be considered the standard for second and further lines of therapy. Response evaluation for present therapies is a challenge. PB Springer YR 2017 FD 2017-10-06 LK http://hdl.handle.net/10668/11796 UL http://hdl.handle.net/10668/11796 LA en NO Gallardo E, Méndez-Vidal MJ, Pérez-Gracia JL, Sepúlveda-Sánchez JM, Campayo M, Chirivella-González I, et al. SEOM clinical guideline for treatment of kidney cancer (2017). Clin Transl Oncol. 2018 Jan;20(1):47-56 DS RISalud RD Apr 10, 2025