TY - JOUR AU - Perkovic, Vlado AU - Jardine, Meg J AU - Neal, Bruce AU - Bompoint, Severine AU - Heerspink, Hiddo J L AU - Charytan, David M AU - Edwards, Robert AU - Agarwal, Rajiv AU - Bakris, George AU - Bull, Scott AU - Cannon, Christopher P AU - Capuano, George AU - Chu, Pei-Ling AU - de Zeeuw, Dick AU - Greene, Tom AU - Levin, Adeera AU - Pollock, Carol AU - Wheeler, David C AU - Yavin, Yshai AU - Zhang, Hong AU - Zinman, Bernard AU - Meininger, Gary AU - Brenner, Barry M AU - Mahaffey, Kenneth W AU - CREDENCE Trial Investigators PY - 2019 DO - 10.1056/NEJMoa1811744 UR - https://hdl.handle.net/10668/26680 T2 - The New England journal of medicine AB - Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium-glucose cotransporter 2 (SGLT2), exploratory results have suggested that... LA - en KW - Aged KW - Canagliflozin KW - Cardiovascular Diseases KW - Creatinine KW - Diabetes Mellitus, Type 2 KW - Diabetic Nephropathies KW - Double-Blind Method KW - Female KW - Follow-Up Studies KW - Glomerular Filtration Rate KW - Humans KW - Kidney Failure, Chronic KW - Male KW - Middle Aged KW - Sodium-Glucose Transporter 2 Inhibitors TI - Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy. TY - research article VL - 380 ER -