RT Journal Article T1 Current Antiarrhythmic Therapy for Nonvalvular Atrial Fibrillation in Spain. Data From the FANTASIIA Registry A1 Roldan Rabadan, Inmaculada A1 Anguita Sanchez, Manuel A1 Marin, Francisco A1 Angustias Quesada, Maria A1 Camacho Siles, Jose A1 Peinado, Rafael A1 Bertomeu, Vicente A1 Cequier Fillat, Angel A1 Badimon, Lina A1 Muniz, Javier A1 FANTASIIA Study Researchers, K1 Nonvalvular atrial fibrillation K1 Antiarrhythmic therapy K1 Cardioversion K1 Ablation K1 FANTASIIA registry K1 Rhythm-control K1 Follow-up K1 European-society K1 Dronedarone K1 Prevention K1 Guidelines K1 Management K1 Countries K1 Prognosis K1 Mortality AB Introduction and objectives: Recently, there have been many developments in the management of nonvalvular atrial fibrillation, antiarrhythmic and anticoagulant therapy, and nonpharmacological treatment, but these developments are not applied immediately in clinical practice. The aim of this study was to identify the overall management and antiarrhythmic therapy used in the current general population of patients with nonvalvular atrial fibrillation in Spain.Methods: A prospective, observational study of 1318 consecutive anticoagulated patients with nonvalvular atrial fibrillation, recruited between June 2013 and March 2014. We analyzed the patients' general characteristics, management, and antiarrhythmic therapy.Results: Mean age was 73.8 + 9.4 years; 42.5% were women. Atrial fibrillation was paroxysmal in 28% of the patients, permanent in 50%, persistent in 17.6%, long-standing persistent in 4.5%, and new-onset in 66 patients (5%). A rhythm control strategy was chosen in 39.4% of the patients and rate control in 60.6%. Beta-blockers were prescribed in 60.2% of the patients, digoxin in 19.5%, and calcium channel antagonists in 10.7%. The antiarrhythmic agents used were amiodarone (12.6%), flecainide (8.9%), propafenone (0.4%), sotalol (0.5%), and dronedarone (2.3%). Cardioversion had been performed previously in 41.9% of the patients, ablation in 3.4%, and atrial appendage closure in 0.2%.Conclusions: Currently, patients with nonvalvular atrial fibrillation in Spain are managed mainly with rate control, and beta-blockers in particular. They receive few antiarrhythmic agents and only a very small number of these patients undergo nonpharmacological treatments. (C) 2015 Sociedad Espanola de Cardiologia. Published by Elsevier Espana, S.L.U. All rights reserved. PB Ediciones doyma s a SN 1885-5857 YR 2016 FD 2016-01-01 LK https://hdl.handle.net/10668/25377 UL https://hdl.handle.net/10668/25377 LA en DS RISalud RD Apr 5, 2025