RT Journal Article
T1 High-Density Lipoproteins and Mediterranean Diet: A Systematic Review
A1 Grao-Cruces, Elena
A1 Varela, Lourdes M.
A1 Martin, Maria E.
A1 Bermudez, Beatriz
A1 Montserrat-de la Paz, Sergio
K1 High-density lipoprotein
K1 Lipidome
K1 Proteome
K1 Mediterranean diet
K1 Olive oil
K1 Lipoproteínas HDL
K1 Lipidómica
K1 Proteoma
K1 Dieta mediterránea
K1 Aceite de oliva
K1 Revisión sistemática
K1 Metaanálisis
AB Cardiovascular disease (CVD) is the leading cause of global mortality and the study of high-density lipoproteins (HDL) particle composition and functionality has become a matter of high interest, particularly in light to the disappointing clinical data for HDL-cholesterol (HDL-C) raising therapies in CVD secondary prevention and the lack of association between HDL-C and the risk of CVD. Recent evidences suggest that HDL composition and functionality could be modulated by diet. The purpose of this systematic review was to investigate the effect of Mediterranean diet (MD) on changes in HDL structure and functionality in humans. A comprehensive search was conducted in four databases (PubMed, Scopus, Cochrane library and Web of Science) and 13 records were chosen. MD showed favorable effects on HDL functionality, particularly by improving HDL cholesterol efflux capacity and decreasing HDL oxidation. In addition, HDL composition and size were influenced by MD. Thus, MD is a protective factor against CVD associated with the improvement of HDL quality and the prevention of HDL dysfunctionality.
PB MDPI
YR 2021
FD 2021-03-16
LK http://hdl.handle.net/10668/4272
UL http://hdl.handle.net/10668/4272
LA en
NO Grao-Cruces E, Varela LM, Martin ME, Bermudez B, Montserrat-de la Paz S. High-Density Lipoproteins and Mediterranean Diet: A Systematic Review. Nutrients. 2021 Mar 16;13(3):955
DS RISalud
RD Apr 13, 2025