%0 Journal Article %A Langefeld, Carl D %A Ainsworth, Hannah C %A Cunninghame Graham, Deborah S %A Kelly, Jennifer A %A Comeau, Mary E %A Marion, Miranda C %A Howard, Timothy D %A Ramos, Paula S %A Croker, Jennifer A %A Morris, David L %A Sandling, Johanna K %A Almlöf, Jonas Carlsson %A Acevedo-Vásquez, Eduardo M %A Alarcón, Graciela S %A Babini, Alejandra M %A Baca, Vicente %A Bengtsson, Anders A %A Berbotto, Guillermo A %A Bijl, Marc %A Brown, Elizabeth E %A Brunner, Hermine I %A Cardiel, Mario H %A Catoggio, Luis %A Cervera, Ricard %A Cucho-Venegas, Jorge M %A Dahlqvist, Solbritt Rantapää %A D'Alfonso, Sandra %A Da Silva, Berta Martins %A de la Rúa Figueroa, Iñigo %A Doria, Andrea %A Edberg, Jeffrey C %A Endreffy, Emőke %A Esquivel-Valerio, Jorge A %A Fortin, Paul R %A Freedman, Barry I %A Frostegård, Johan %A García, Mercedes A %A de la Torre, Ignacio García %A Gilkeson, Gary S %A Gladman, Dafna D %A Gunnarsson, Iva %A Guthridge, Joel M %A Huggins, Jennifer L %A James, Judith A %A Kallenberg, Cees G M %A Kamen, Diane L %A Karp, David R %A Kaufman, Kenneth M %A Kottyan, Leah C %A Kovács, László %A Laustrup, Helle %A Lauwerys, Bernard R %A Li, Quan-Zhen %A Maradiaga-Ceceña, Marco A %A Martín, Javier %A McCune, Joseph M %A McWilliams, David R %A Merrill, Joan T %A Miranda, Pedro %A Moctezuma, José F %A Nath, Swapan K %A Niewold, Timothy B %A Orozco, Lorena %A Ortego-Centeno, Norberto %A Petri, Michelle %A Pineau, Christian A %A Pons-Estel, Bernardo A %A Pope, Janet %A Raj, Prithvi %A Ramsey-Goldman, Rosalind %A Reveille, John D %A Russell, Laurie P %A Sabio, José M %A Aguilar-Salinas, Carlos A %A Scherbarth, Hugo R %A Scorza, Raffaella %A Seldin, Michael F %A Sjöwall, Christopher %A Svenungsson, Elisabet %A Thompson, Susan D %A Toloza, Sergio M A %A Truedsson, Lennart %A Tusié-Luna, Teresa %A Vasconcelos, Carlos %A Vilá, Luis M %A Wallace, Daniel J %A Weisman, Michael H %A Wither, Joan E %A Bhangale, Tushar %A Oksenberg, Jorge R %A Rioux, John D %A Gregersen, Peter K %A Syvänen, Ann-Christine %A Rönnblom, Lars %A Criswell, Lindsey A %A Jacob, Chaim O %A Sivils, Kathy L %A Tsao, Betty P %A Schanberg, Laura E %A Behrens, Timothy W %A Silverman, Earl D %A Alarcón-Riquelme, Marta E %A Kimberly, Robert P %A Harley, John B %A Wakeland, Edward K %A Graham, Robert R %A Gaffney, Patrick M %A Vyse, Timothy J %T Transancestral mapping and genetic load in systemic lupus erythematosus. %D 2017 %U http://hdl.handle.net/10668/11414 %X Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparities. We report a large transancestral association study of SLE using Immunochip genotype data from 27,574 individuals of European (EA), African (AA) and Hispanic Amerindian (HA) ancestry. We identify 58 distinct non-HLA regions in EA, 9 in AA and 16 in HA (∼50% of these regions have multiple independent associations); these include 24 novel SLE regions (P %~