TY  - JOUR
AU  - Aliaga-Gaspar, Pablo
AU  - Hurtado-Guerrero, Isaac
AU  - Ciano-Petersen, Nicolas Lundahl
AU  - Urbaneja, Patricia
AU  - Brichette-Mieg, Isabel
AU  - Reyes, Virginia
AU  - Rodriguez-Bada, Jose Luis
AU  - Alvarez-Lafuente, Roberto
AU  - Arroyo, Rafael
AU  - Quintana, Ester
AU  - Ramió-Torrentà, Lluis
AU  - Alonso, Ana
AU  - Leyva, Laura
AU  - Fernández, Oscar
AU  - Oliver-Martos, Begoña
PY  - 2021
DO  - 10.3389/fimmu.2021.778204
UR  - http://hdl.handle.net/10668/4025
T2  - Frontiers in Immunology
AB  - Purpose: Interferon beta receptor 2 subunit (IFNAR2) can be produced as a transmembrane protein, but also as a soluble form (sIFNAR2) generated by alternative splicing or proteolytic cleavage, which has both agonist and antagonist activities for...
LA  - en
PB  - Frontiers
KW  - Alternative splicing
KW  - Soluble receptors
KW  - IFNAR
KW  - Interferon beta
KW  - Multiple sclerosis
KW  - Empalme alternativo
KW  - Receptor de interferones alfa y beta
KW  - Interferón beta
KW  - Esclerosis múltiple
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::RNA Processing, Post-Transcriptional::RNA Splicing::Alternative Splicing
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Monitoring, Physiologic::Drug Monitoring
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal...
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Interferons::Interferon Type I::Interferon-beta
KW  - Medical Subject Headings::Check Tags::Male
KW  - Multiple Sclerosis, Relapsing-Remitting
KW  - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Cytokine::Receptors, Interferon::Receptor, Interferon alpha-beta
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome
TI  - Soluble Receptor Isoform of IFN-Beta (sIFNAR2) in Multiple Sclerosis Patients and Their Association With the Clinical Response to IFN-Beta Treatment
TY  - research article
ER  -