RT Journal Article T1 Depression, anxiety, and stress in oral lichen planus: a systematic review and meta-analysis. A1 De Porras-Carrique, Teresa A1 González-Moles, Miguel Ángel A1 Warnakulasuriya, Saman A1 Ramos-García, Pablo K1 Anxiety K1 Depression K1 Meta-analysis K1 Oral lichen planus K1 Stress K1 Systematic review AB We present this systematic review and meta-analyses to evaluate current evidence on the prevalence of depression, anxiety, and stress in patients with oral lichen planus and their magnitude of association. We searched PubMed, Embase, Web of Science, Scopus, PsycInfo, and Google Scholar for studies published before January 2021. We evaluated the quality of studies using a specific method for systematic reviews addressing prevalence questions, designed by the Joanna Briggs Institute. We carried out meta-analyses and performed heterogeneity, subgroups, meta-regression, and small-study effects analyses. Fifty-one studies (which recruited 6,815 patients) met the inclusion criteria. Our results reveal a high prevalence of depression (31.19%), anxiety (54.76%), and stress (41.10%) in oral lichen planus. Furthermore, OLP patients presented a significantly higher relative frequency than control group without OLP for depression (OR = 6.15, 95% CI = 2.73-13.89, p  Our systematic review and meta-analysis show that patients with OLP suffer a higher prevalence of depression, anxiety, and stress, being more frequent than in general population. Clinical relevance In the dental clinic, especially dentists should be aware of depression, anxiety, and stress in OLP patients to achieve a correct referral. YR 2021 FD 2021-08-30 LK http://hdl.handle.net/10668/18482 UL http://hdl.handle.net/10668/18482 LA en DS RISalud RD Apr 5, 2025