TY  - JOUR
AU  - Robles-Vera, Iñaki
AU  - de la Visitación, Néstor
AU  - Toral, Marta
AU  - Sánchez, Manuel
AU  - Gómez-Guzmán, Manuel
AU  - Jiménez, Rosario
AU  - Romero, Miguel
AU  - Duarte, Juan
PY  - 2020
DO  - 10.1016/j.biopha.2020.111189
SN  - 0753-3322
UR  - http://hdl.handle.net/10668/4216
T2  - Biomedicine & Pharmacotherapy
AB  - Microbiota has a role in the host blood pressure (BP) regulation. The immunosuppressive drug mofetil mycophenolate (MMF) ameliorates hypertension. The present study analyzes whether MMF improves dysbiosis in a genetic model of hypertension. Twenty...
LA  - en
PB  - Elsevier Masson
KW  - Mycophenolate
KW  - Gut dysbiosis
KW  - Hypertension
KW  - Oxidative stress
KW  - Inflammation
KW  - SHR
KW  - Lymph nodes
KW  - Cytokines
KW  - Ácido micofenólico
KW  - Disbiosis
KW  - Hipertensión
KW  - Estrés oxidativo
KW  - Inflamación
KW  - Ratas endogámicas SHR
KW  - Ganglios linfáticos
KW  - Citocinas
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Cardiovascular Agents::Antihypertensive Agents
KW  - Medical Subject Headings::Anatomy::Cardiovascular System::Blood Vessels::Arteries::Aorta::Aorta, Thoracic
KW  - Medical Subject Headings::Organisms::Bacteria
KW  - Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Hemodynamics::Blood Pressure
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured
KW  - Medical Subject Headings::Anatomy::Digestive System::Gastrointestinal Tract::Intestines::Intestine, Large::Colon
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines
KW  - Medical Subject Headings::Diseases::Animal Diseases::Disease Models, Animal
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Dysbiosis
KW  - Medical Subject Headings::Diseases::Cardiovascular Diseases::Vascular Diseases::Hypertension
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Inflammation Mediators
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids, Acyclic::Caproates::Mycophenolic Acid
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Electrophysiological Phenomena::Electrophysiological Processes::Neuroimmunomodulation
KW  - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain::Prosencephalon::Diencephalon::Hypothalamus::Hypothalamus, Anterior::Paraventricular Hypothalamic Nucleus
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Inbred Strains::Rats, Inbred Strains::Rats, Inbred SHR
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Inbred Strains::Rats, Inbred Strains::Rats, Inbred WKY
KW  - Medical Subject Headings::Anatomy::Nervous System::Peripheral Nervous System::Autonomic Nervous System::Sympathetic Nervous System
KW  - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Organisms::Bacteria::Bacteria, Anaerobic
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Biological::Models, Genetic
KW  - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::T-Lymphocyte Subsets::T-Lymphocytes, Regulatory
KW  - Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Volatile::Butyrates
KW  - Medical Subject Headings::Phenomena and Processes::Microbiological Phenomena::Microbiota
KW  - Medical Subject Headings::Anatomy::Cardiovascular System::Blood Vessels::Arteries::Aorta
KW  - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain
KW  - Medical Subject Headings::Organisms::Bacteria::Bacteroidetes
KW  - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hypothalamus
KW  - Medical Subject Headings::Anatomy::Tissues::Lymphoid Tissue::Lymph Nodes
KW  - Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Volatile::Acetates
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Hydroxy Acids::Lactates
TI  - Mycophenolate mediated remodeling of gut microbiota and improvement of gut-brain axis in spontaneously hypertensive rats
TY  - research article
ER  -