TY - JOUR AU - Escobedo-Cousin, Michelle AU - Jackson, Nicola AU - Laza-Briviesca, Raquel AU - Ariza-McNaughton, Linda AU - Luevano, Martha AU - Derniame, Sophie AU - Querol, Sergio AU - Blundell, Michael AU - Thrasher, Adrian AU - Soria, Bernat AU - Cooper, Nichola AU - Bonnet, Dominique AU - Madrigal, Alejandro AU - Saudemont, Aurore PY - 2015 DO - 10.1371/journal.pone.0138623 UR - http://hdl.handle.net/10668/2248 T2 - PloS ONE AB - Cord blood (CB) is increasingly used as a source of hematopoietic stem cells (HSC) for transplantation. Low incidence and severity of graft-versus-host disease (GvHD) and a robust graft-versus-leukemia (GvL) effect are observed following CB... LA - en PB - Public Library of Science KW - NK cells KW - Hematopoietic stem cells KW - Mouse models KW - Integrins KW - T cells KW - Gene expression KW - Flow cytometry KW - Cytotoxic T cells KW - Células Asesinas Naturales KW - Células Madre Hematopoyéticas KW - Células Madre Embrionarias de Ratones KW - Integrinas KW - Expresión Génica KW - Citometría de flujo KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Movement KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Chemotactic Factors::Chemokines::Chemokines, CXC::Chemokine CXCL9 KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Transplantation::Cell Transplantation::Stem Cell Transplantation::Cord Blood Stem Cell Transplantation KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Division::Cytokinesis KW - Medical Subject Headings::Anatomy::Embryonic Structures::Fetus::Fetal Blood KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation KW - Medical Subject Headings::Diseases::Immune System Diseases::Graft vs Host Disease KW - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immune System Processes::Transplantation Immunology::Graft vs Host Reaction::Graft vs Tumor Effect::Graft vs Leukemia Effect KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Transplantation::Cell Transplantation::Stem Cell Transplantation::Hematopoietic Stem Cell Transplantation KW - Medical Subject Headings::Anatomy::Hemic and Immune Systems::Hematopoietic System::Bone Marrow Cells::Hematopoietic Stem Cells KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-15 KW - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::Killer Cells, Natural KW - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Inbred Strains::Mice, Inbred NOD KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Mutant Strains::Mice, SCID KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Hybridization::Oligonucleotide Array Sequence Analysis KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Recombinant Proteins KW - Medical Subject Headings::Anatomy::Cells::Stem Cells KW - Animals TI - Natural Killer Cells Improve Hematopoietic Stem Cell Engraftment by Increasing Stem Cell Clonogenicity In Vitro and in a Humanized Mouse Model. TY - research article ER -