RT Journal Article
T1 Safety of Early Carotid Artery Stenting for Symptomatic Stenosis in Daily Practice.
A1 Alcalde-Lopez, Jesus
A1 Zapata-Arriaza, Elena
A1 Cayuela, Aurelio
A1 Moniche, Francisco
A1 Escudero-Martinez, Irene
A1 Ortega-Quintanilla, Joaquin
A1 de-Torres-Chacon, Reyes
A1 Montaner, Joan
A1 Mayol, Antonio
A1 Gonzalez, Alejandro
K1 Amaurosis fugax
K1 Angioplasty
K1 Carotid
K1 Stent
K1 Stroke
K1 TIA
AB In 2006, the American Heart Association recommended that for preference carotid endarterectomy (CEA) or, alternatively, carotid angioplasty and stenting (CAS) for symptomatic carotid artery stenosis should ideally occur within 14 days of an ischaemic event. The aim was to determine the safety of CAS according to those recommendations in daily practice. A retrospective analysis was performed of all consecutive patients (2000-16), with ipsilateral carotid symptoms who underwent CAS for extracranial carotid stenosis ≥70%, who were previously included in a prospective database. Thirty day morbidity was assessed (any stroke without transient ischaemic attack [TIA]/amaurosis fugax), along with mortality of the procedure in the early (≤14 days after stroke onset) and delayed phases (15-180 days after stroke onset). Patients who received CAS and/or mechanical thrombectomy for acute ischaemic stroke treatment were not included. In total, 1227 patients with symptomatic carotid stenosis who underwent CAS were identified. Early and delayed CAS was performed in 291 and 936 patients, respectively. Morbidity (any stroke) and mortality was 2.2% (n = 27) in the whole cohort (n = 8 [2.7%] in early vs. n = 19 [2%] in delayed CAS; p = .47). There were no differences in morbidity between early and delayed CAS regarding TIA (n = 15 vs. 36 [5.2% vs. 3.9%]; p = .33), minor stroke (n = 4 vs. 5 [1.4% vs. 0.5%]; p = .14), or major stroke (n = 2 vs. 6 [0.7% vs. 0.6%]; p = .59). Two patients (0.7%) died after early CAS and eight (0.9%) after delayed CAS (p = .56). CAS may be safely performed in the early phase after an ischaemic stroke with low clinical complication rates. Further studies are needed to validate CAS safety conducted even earlier in the acute phase of ischaemic stroke.
PB Elsevier Ltd
YR 2018
FD 2018
LK http://hdl.handle.net/10668/12899
UL http://hdl.handle.net/10668/12899
LA en
NO Alcalde-López J, Zapata-Arriaza E, Cayuela A, Moniche F, Escudero-Martínez I, Ortega-Quintanilla J, et al. Safety of Early Carotid Artery Stenting for Symptomatic Stenosis in Daily Practice. Eur J Vasc Endovasc Surg. 2018 Dec;56(6):776-782.
DS RISalud
RD Aug 8, 2025