RT Journal Article
T1 The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case-control study, Spain, 2013/14 and 2014/15
A1 Dominguez, A.
A1 Soldevila, N.
A1 Toledo, D.
A1 Godoy, P.
A1 Espejo, E.
A1 Fernandez, M. A.
A1 Mayoral, J. M.
A1 Castilla, J.
A1 Egurrola, M.
A1 Tamames, S.
A1 Astray, J.
A1 Morales-Suarez-Varela, M.
A1 Project PI12-02079, 
K1 Laboratory-confirmed influenza
K1 Screening method
K1 United-states
K1 New-zealand
K1 Population
K1 Auckland
K1 Navarre
K1 Impact
AB Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged >= 65 years in Spain. A multicentre case-control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged >= 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional logistic regression. A total of 728 cases and 1,826 matched controls were included in the study. Overall VE was 36% (95% confidence interval (CI): 22-47). VE was 51% (95% CI: 15-71) in patients without high-risk medical conditions and 30% (95% CI: 14-44) in patients with them. VE was 39% (95% CI: 20-53) in patients aged 65-79 years and 34% (95% CI: 11-51) in patients aged >= 80 years, and was greater against the influenza A(H1N1) pdm0(9) subtype than the A(H3N2) subtype. Influenza vaccination was effective in preventing hospitalisations of elderly individuals.
PB Eur centre dis prevention & control
SN 1560-7917
YR 2017
FD 2017-08-24
LK http://hdl.handle.net/10668/19203
UL http://hdl.handle.net/10668/19203
LA en
DS RISalud
RD Apr 10, 2025