RT Journal Article
T1 Targeted treatment approaches in refractory germ cell tumors.
A1 Galvez-Carvajal, Laura
A1 Sanchez-Muñoz, Alfonso
A1 Ribelles, Nuria
A1 Saez, Maribel
A1 Baena, Javier
A1 Ruiz, Sofia
A1 Ithurbisquy, Catherine
A1 Alba, Emilio
K1 Germ cell tumors
K1 Targeted therapy
K1 Testicular tumors
AB Germ cell tumors (GCTs) are the most common type of solid tumor amongst patients between 15 and 35 years of age. They are also one of the types of tumor with the highest cure rate, due to their high sensitivity to cisplatin based chemotherapy. Nonetheless, around 15-20% of metastatic patients will not have curative options after a relapse on the first and second line. This proves that new therapeutic options for these refractory GCTs patients need to be developed. This article offers a bibliographic review of all studies using targeted treatment or immunotherapy for refractory GCTs patients.
YR 2019
FD 2019-09-25
LK http://hdl.handle.net/10668/15022
UL http://hdl.handle.net/10668/15022
LA en
DS RISalud
RD Apr 7, 2025