TY - JOUR AU - Quintanal-Villalonga, Álvaro AU - Ojeda-Márquez, Laura AU - Marrugal, Ángela AU - Yagüe, Patricia AU - Ponce-Aix, Santiago AU - Salinas, Ana AU - Carnero, Amancio AU - Ferrer, Irene AU - Molina-Pinelo, Sonia AU - Paz-Ares, Luis PY - 2018 DO - 10.1038/s41598-018-20570-3 UR - http://hdl.handle.net/10668/12085 T2 - Scientific reports AB - The FGFR4-388Arg variant has been related to poor prognosis in several types of cancer, including lung cancer. The mechanism underlying this association has not been addressed in detail in patients with this pathology. Here, we report that this FGFR4... LA - en KW - Animals KW - Antigens, CD KW - Cadherins KW - Carcinoma, Non-Small-Cell Lung KW - Cell Line, Tumor KW - Disease Progression KW - Epithelial-Mesenchymal Transition KW - Female KW - Gene Expression Regulation, Neoplastic KW - Heterografts KW - Humans KW - Lung Neoplasms KW - Male KW - Mice KW - Mice, Nude KW - Mitogen-Activated Protein Kinases KW - Mutation KW - Nuclear Proteins KW - Prognosis KW - Receptor, Fibroblast Growth Factor, Type 4 KW - STAT3 Transcription Factor KW - Snail Family Transcription Factors KW - Survival Analysis KW - Twist-Related Protein 1 KW - Vimentin TI - The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction. TY - research article VL - 8 ER -