RT Journal Article
T1 Association between Vitamin Intake during Pregnancy and Risk of Small for Gestational Age
A1 Salcedo-Bellido, Inmaculada
A1 Miguel Martinez-Galiano, Juan
A1 Olmedo-Requena, Rocio
A1 Mozas-Moreno, Juan
A1 Bueno-Cavanillas, Aurora
A1 Jimenez-Moleon, Jose J.
A1 Delgado-Rodriguez, Miguel
K1 maternal nutrition
K1 dietary vitamins intake
K1 pregnancy
K1 small for gestational age
K1 Birth-weight infants
K1 Neonatal outcomes
K1 Maternal intake
K1 Women
K1 Diet
K1 Preterm
K1 Health
K1 Folate
K1 Fetal
K1 Supplements
AB Pregnancy increases the requirements of certain nutrients, such as vitamins, to provide nutrition for the newborn. The aim was to analyze the association between dietary intake of vitamins during pregnancy and risk of having a small for gestational age (SGA) newborn. A matched case-control study was conducted (518 cases and 518 controls of pregnant women) in Spain. Dietary vitamin intake during pregnancy was assessed using a validated food frequency questionnaire, categorized into quintiles. Odds ratios (ORs) and their 95% confidence intervals (CI) were estimated with conditional regression logistic models. A protective association was observed between maternal dietary intake of vitamins A and D and SGA. For vitamin B3 and B6, the observed protective effect was maintained after adjusting for potential confounding factors. For vitamin B9, we found only an effect in quintiles 3 and 4 (OR = 0.64; 95% CI, 0.41-1.00; OR = 0.58; 95% CI, 0.37-0.91). Protective effect for vitamin B12 was observed in 4th and 5th quintiles (OR = 0.61; 95% CI, 0.39-0.95; OR = 0.68; 95% CI, 0.43-1.04). No associations were detected between dietary intake of vitamins B2, E and C intake and SGA. Our results suggest a positive association between dietary vitamin intake during pregnancy and the weight of the newborn, although more studies are necessary and there could be a ceiling effect for higher intakes of some vitamins cannot be discarded.
PB Mdpi
SN 2072-6643
YR 2017
FD 2017-12-01
LK http://hdl.handle.net/10668/19318
UL http://hdl.handle.net/10668/19318
LA en
DS RISalud
RD Apr 11, 2025