RT Journal Article
T1 Community-Acquired Pneumonia among Patients with COPD in Spain from 2016 to 2019. Cohort Study Assessing Sex Differences in the Incidence and Outcomes Using Hospital Discharge Data
A1 de Miguel-Diez, Javier
A1 Lopez-Herranz, Marta
A1 Hernandez-Barrera, Valentin
A1 de Miguel-Yanes, Jose M.
A1 Perez-Farinos, Napoleon
A1 Wärnberg, Julia
A1 Carabantes-Alarcon, David
A1 Jimenez-Garcia, Rodrigo
A1 Lopez-de-Andres, Ana
K1 Community-acquired pneumonia
K1 COPD
K1 Sex
K1 Incidence
K1 In-hospital mortality
K1 Neumonía
K1 Infecciones comunitarias adquiridas
K1 Enfermedad pulmonar obstructiva crónica
K1 Diferenciación sexual
K1 Incidencia
K1 Mortalidad hospitalaria
AB Background: To describe and analyze the incidence and hospital outcomes of patients admitted with community-acquired pneumonia (CAP) according to Chronic Obstructive Pulmonary Disease (COPD) status and sex in Spanish hospitals from 2016 to 2019. Methods: We conducted a cohort study using national hospital discharge data of all patients ≥40 years with CAP. Results: A total of 500,833 patients (59.0% men) was identified. Incidence of CAP increased over time. Age adjusted incidence was 4.42-times higher in COPD patients. In-hospital mortality (IHM) was lower in men and women with COPD than in those without COPD (14.41% vs. 10.70% in men; 11.12% vs. 8.58%. in women; p < 0.001). The risk of dying in hospital increased with age, presence of several comorbidities (excluding T2DM that was a protective factor), and need for mechanical ventilation (non-invasive and invasive) during admission, irrespective of sex. Over time, the IHM decreased significantly in men and women with COPD. Men with COPD were significantly more likely to die in hospital than were COPD women (OR 1.13; 95% CI 1.07–1.21). Conclusions: Incidence of CAP was higher among subjects with COPD, although the effect of COPD was higher in men than in women. By contrast, IHM was lower in COPD patients, but men with COPD were significantly more likely to die in hospital than were COPD women.
PB MDPI
YR 2021
FD 2021-10-23
LK http://hdl.handle.net/10668/3952
UL http://hdl.handle.net/10668/3952
LA en
NO de Miguel-Diez J, Lopez-Herranz M, Hernandez-Barrera V, de Miguel-Yanes JM, Perez-Farinos N, Wärnberg J, et al. Community-Acquired Pneumonia among Patients with COPD in Spain from 2016 to 2019. Cohort Study Assessing Sex Differences in the Incidence and Outcomes Using Hospital Discharge Data. J Clin Med. 2021 Oct 23;10(21):4889
DS RISalud
RD Apr 5, 2025