TY - JOUR AU - Romero-Garcia, Raquel AU - Gomez-Jaramillo, Laura AU - Mateos, Rosa Maria AU - Jimenez-Gomez, Gema AU - Pedreño-Horrillo, Nuria AU - Foncubierta, Esther AU - Rodriguez-Gutierrez, Juan Francisco AU - Garzon, Sebastian AU - Mora-Lopez, Francisco AU - Rodriguez, Carmen AU - Valor, Luis M AU - Campos-Caro, Antonio PY - 2020 DO - 10.1038/s41598-020-72946-z UR - http://hdl.handle.net/10668/16333 T2 - Scientific reports AB - Multiple myeloma (MM) is a B-cell neoplasm that is characterized by the accumulation of malignant plasma cells in the bone marrow. The transcription factor PRDM1 is a master regulator of plasma cell development and is considered to be an... LA - en PB - Nature Publishing Group KW - Área de Gestión Sanitaria de Jerez, Costa Noroeste y Sierra de Cádiz KW - Apoptosis KW - Cell Line, Tumor KW - DNA Methylation KW - Down-Regulation KW - Epigenesis, Genetic KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Multiple Myeloma KW - Positive Regulatory Domain I-Binding Factor 1 KW - Promoter Regions, Genetic TI - Differential epigenetic regulation between the alternative promoters, PRDM1α and PRDM1β, of the tumour suppressor gene PRDM1 in human multiple myeloma cells. TY - research article VL - 10 ER -