RT Journal Article
T1 Oxidative stress: Normal pregnancy versus preeclampsia.
A1 Chiarello, Delia I
A1 Abad, Cilia
A1 Rojas, Deliana
A1 Toledo, Fernando
A1 Vázquez, Carmen M
A1 Mate, Alfonso
A1 Sobrevia, Luis
A1 Marín, Reinaldo
K1 Oxidative stress
K1 Preeclampsia
K1 RNS
K1 ROS
AB The role of oxidative stress in the physiopathology of human pregnancy is of particular interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a normal systemic inflammatory response, which results in high amounts of circulating reactive oxygen species (ROS) and reactive nitrogen species (RNS). Both ROS and RNS play an important role as secondary messengers in many intracellular signalling cascades. However, they can also exert critical effects on pathological processes involving the pregnant woman. ROS, RNS and antioxidants establish a balance that determines the oxidation status of animals and humans. This review focuses on the mechanism of oxidative stress in pregnancy as well as its involvement and consequences on the human pregnancy-specific clinical syndrome preeclampsia.
YR 2018
FD 2018-12-24
LK http://hdl.handle.net/10668/13359
UL http://hdl.handle.net/10668/13359
LA en
DS RISalud
RD Apr 8, 2025