RT Journal Article
T1 Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala
A1 Pineda, Rafael
A1 Torres, Encarnacion
A1 Tena-Sempere, Manuel
K1 metabolism
K1 amygdala
K1 estrogens
K1 neuropeptides
K1 kisspeptins
K1 food intake
K1 energy balance
K1 body weight
K1 Estrogen-receptor-alpha
K1 Messenger-rna expression
K1 Metabolic-control
K1 Gene-expression
K1 Medial amygdala
K1 Food-intake
K1 Physiological roles
K1 Kiss1 expression
K1 Sex-differences
K1 Body-weight
AB Body energy and metabolic homeostasis are exquisitely controlled by multiple, often overlapping regulatory mechanisms, which permit the tight adjustment between fuel reserves, internal needs, and environmental (e.g., nutritional) conditions. As such, this function is sensitive to and closely connected with other relevant bodily systems, including reproduction and gonadal function. The aim of this mini-review article is to summarize the most salient experimental data supporting a role of the amygdala as a key brain region for emotional learning and behavior, including reward processing, in the physiological control of feeding and energy balance. In particular, a major focus will be placed on the putative interplay between reproductive signals and amygdala pathways, as it pertains to the control of metabolism, as complementary, extrahypothalamic circuit for the integral control of energy balance and gonadal function.
PB Mdpi
YR 2021
FD 2021-12-01
LK https://hdl.handle.net/10668/25632
UL https://hdl.handle.net/10668/25632
LA en
DS RISalud
RD Apr 6, 2025