RT Generic T1 Clinical practice guidelines and consensus for the screening of breast cancer: A systematic appraisal of their quality and reporting A1 Maes-Carballo, Marta A1 Mignini, Luciano A1 Martin-Diaz, Manuel A1 Bueno-Cavanillas, Aurora A1 Khan, Khalid Saeed K1 AGREE II K1 Breast cancer screening K1 Clinical practice guidelines K1 Consensus statements K1 Quality K1 Recommendations AB Introduction Clinical practice guidelines (CPGs) and consensus statements (CSs) are being promoted to provide high-quality healthcare guidance. This systematic review has assessed the breast cancer (BC) screening CPGs and CSs quality and reporting. Methods A search of bibliographic databases (MEDLINE, Embase, Web of Science, Scopus and CDSR), 12 guideline databases and 51 professional society websites was performed without language restrictions from January 2017 to June 2020, following prospective registration (Prospero no.: CRD42020203807). AGREE II (% of maximum score) and RIGHT (% of total 35 items) appraised quality and reporting individually, extracting data in duplicate; reviewer agreement was 98% and 93%, respectively. Results Forty guidances with median overall quality and reporting 51% (interquartile range [IQR] 39-63) and 48% (IQR 35-65), respectively. Twenty-two (55%) and 20 (50%) did not reach the minimum standards (scores <50%). The guidances thatdeployed systematic reviews had better quality (74.2% vs. 46.9%; p = 0.001) andreporting (80.5% vs. 42.6%; p = 0.001). Guidances reporting a tool referral scoredbetter (AGREE II: 72.8% vs. 43.1%, p = 0.002; RIGHT: 75.0% vs. 46.9%, p = 0.004).Conclusion: BC screening CPGs and CSs suffered poor quality and reporting. Morethan half did not reach the minimum standards. They would improve if systematicreviews were used to underpin the recommendations made. PB Wiley SN 0961-5423 YR 2022 FD 2022-03-08 LK https://hdl.handle.net/10668/25964 UL https://hdl.handle.net/10668/25964 LA en DS RISalud RD Sep 23, 2025