%0 Journal Article
%A Beaumont, Javier
%A López, Begoña
%A Ravassa, Susana
%A Hermida, Nerea
%A San José, Gorka
%A Gallego, Idoia
%A Valencia, Félix
%A Gómez-Doblas, Juan José
%A de Teresa, Eduardo
%A Díez, Javier
%A González, Arantxa
%T MicroRNA-19b is a potential biomarker of increased myocardial collagen cross-linking in patients with aortic stenosis and heart failure.
%D 2017
%U http://hdl.handle.net/10668/10778
%X This study analyzed the potential associations of 7 myocardial fibrosis-related microRNAs with the quality of the collagen network (e.g., the degree of collagen fibril cross-linking or CCL) and the enzyme lysyl oxidase (LOX) responsible for CCL in 28 patients with severe aortic stenosis (AS) of whom 46% had a diagnosis of chronic heart failure (HF). MicroRNA expression was analyzed in myocardial and blood samples. From the studied microRNAs only miR-19b presented a direct correlation (p 
%~