TY - JOUR AU - Reck, Martin AU - Paz-Ares, Luis AU - Bidoli, Paolo AU - Cappuzzo, Federico AU - Dakhil, Shaker AU - Moro-Sibilot, Denis AU - Borghaei, Hossein AU - Johnson, Melissa AU - Jotte, Robert AU - Pennell, Nathan A AU - Shepherd, Frances A AU - Tsao, Anne AU - Thomas, Michael AU - Carter, Gebra Cuyun AU - Chan-Diehl, Faye AU - Alexandris, Ekaterine AU - Lee, Pablo AU - Zimmermann, Annamaria AU - Sashegyi, Andreas AU - PĂ©rol, Maurice PY - 2017 DO - 10.1016/j.lungcan.2017.07.038 UR - http://hdl.handle.net/10668/11859 T2 - Lung cancer (Amsterdam, Netherlands) AB - The REVEL study demonstrated improved efficacy for patients with advanced non-small cell lung cancer treated with ramucirumab plus docetaxel, independent of histology. This exploratory analysis characterized the treatment effect in REVEL patients who... LA - en KW - Angiogenesis KW - Clinical trial KW - Docetaxel KW - Histology KW - Human monoclonal antibody KW - Non-small cell lung cancer (NSCLC) KW - Phase 3 clinical trial KW - Ramucirumab KW - Refractory patients KW - Vascular endothelial growth factor (VEGF) KW - Adult KW - Aged KW - Aged, 80 and over KW - Antibodies, Monoclonal KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Combined Chemotherapy Protocols KW - Carcinoma, Non-Small-Cell Lung KW - Disease Progression KW - Docetaxel KW - Drug Resistance, Neoplasm KW - Female KW - Humans KW - Kaplan-Meier Estimate KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Neoplasm Staging KW - Quality of Life KW - Retreatment KW - Taxoids KW - Treatment Outcome KW - Young Adult TI - Outcomes in patients with aggressive or refractory disease from REVEL: A randomized phase III study of docetaxel with ramucirumab or placebo for second-line treatment of stage IV non-small-cell lung cancer. TY - research article VL - 112 ER -