RT Journal Article T1 Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships. A1 García-Medina, Manuel A1 García-Medina, Jose Javier A1 Garrido-Fernández, Pablo A1 Galván-Espinosa, Jose A1 Martín-Molina, Jesús A1 García-Maturana, Carlos A1 Pérez-Pardo, Sergio A1 Pinazo-Durán, Maria Dolores K1 Central corneal thickness K1 Intraocular pressure K1 Population study K1 Glaucoma K1 Myopia K1 Córnea K1 Miopía K1 Presión intraocular K1 Intervalos de confianza K1 Ojo AB Objective:To determine the values of, and study the relationships among, central corneal thickness (CCT), intraocular pressure (IOP), and degree of myopia (DM) in an adult myopic population aged 20 to 40 years in Almeria (southeast Spain). To our knowledge this is first study of this kind in this region.Methods:An observational, descriptive, cross-sectional study was done in which a sample of 310 myopic patients (620 eyes) aged 20 to 40 years was selected by gender- and age-stratified sampling, which was proportionally fixed to the size of the population strata for which a 20% prevalence of myopia, 5% epsilon, and a 95% confidence interval were hypothesized. We studied IOP, CCT, and DM and their relationships by calculating the mean, standard deviation, 95% confidence interval for the mean, median, Fisher’s asymmetry coefficient, range (maximum, minimum), and the Brown-Forsythe’s robust test for each variable (IOP, CCT, and DM).Results:In the adult myopic population of Almeria aged 20 to 40 years (mean of 29.8), the mean overall CCT was 550.12 μm. The corneas of men were thicker than those of women (P = 0.014). CCT was stable as no significant differences were seen in the 20- to 40-year-old subjects’ CCT values. The mean overall IOP was 13.60 mmHg. Men had a higher IOP than women (P = 0.002). Subjects over 30 years (13.83) had a higher IOP than those under 30 (13.38) (P = 0.04). The mean overall DM was −4.18 diopters. Men had less myopia than women (P < 0.001). Myopia was stable in the 20- to 40-year-old study population (P = 0.089). A linear relationship was found between CCT and IOP (R2 = 0.152, P ≤ 0.001). CCT influenced the IOP value by 15.2%. However no linear relationship between DM and IOP, or between CCT and DM, was found.Conclusions:CCT was found to be similar to that reported in other studies in different populations. IOP tends to increase after the age of 30 and is not accounted for by alterations in CCT values. PB Dovepress SN 1177-5467 YR 2011 FD 2011-02-28 LK http://hdl.handle.net/10668/2092 UL http://hdl.handle.net/10668/2092 LA en NO García-Medina M, García-Medina JJ, Garrido-Fernández P, Galván-Espinosa J, Martín-Molina J, García-Maturana C, et al. Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships. Clin Ophthalmol 2011; 5:249-58 DS RISalud RD Apr 11, 2025