RT Journal Article
T1 Probiotics to prevent necrotising enterocolitis and nosocomial infection in very low birth weight preterm infants.
A1 Uberos, J
A1 Aguilera-Rodríguez, E
A1 Jerez-Calero, A
A1 Molina-Oya, M
A1 Molina-Carballo, A
A1 Narbona-López, E
K1 Lactobacillus
K1 Lactobacillus acidophillus
K1 Lactobacillus bifidum
K1 rhamnosus GG
K1 LGG Lactobacillus rhamnosus GG
K1 NEC necrotising enterocolitis
K1 VLBW very low birth weight
K1 Late-onset sepsis
K1 Necrotising enterocolitis
K1 Probiotics
K1 Very low birth weight infants
AB The aim of the study was to determine whether routine probiotic supplementation (RPS) with Lactobacillus rhamnosus GG (LGG) or Lactobacillus acidophilus +Lactobacillus bifidum is associated with reduced risk of necrotising enterocolitis (NEC)≥Stage II in preterm neonates born at ≤32 weeks' gestation. We conducted a retrospective cohort study on the effect of probiotic supplementation in very low birth weight infants in our neonatal unit by comparing two periods: before and after supplementation. The incidence of NEC≥Stage II, late-onset sepsis and all-cause mortality was compared for an equal period 'before' (Period I) and 'after' (Period II) RPS with LGG or L. acidophillus+L. bifidum. Multivariate logistic regression analysis was conducted to adjust for relevant confounders. The study population was composed of 261 neonates (Period I v. II: 134 v. 127) with comparable gestation duration and birth weights. In
YR 2017
FD 2017-04-26
LK http://hdl.handle.net/10668/11132
UL http://hdl.handle.net/10668/11132
LA en
DS RISalud
RD Apr 7, 2025