%0 Journal Article
%A Uberos, J
%A Aguilera-Rodríguez, E
%A Jerez-Calero, A
%A Molina-Oya, M
%A Molina-Carballo, A
%A Narbona-López, E
%T Probiotics to prevent necrotising enterocolitis and nosocomial infection in very low birth weight preterm infants.
%D 2017
%U http://hdl.handle.net/10668/11132
%X The aim of the study was to determine whether routine probiotic supplementation (RPS) with Lactobacillus rhamnosus GG (LGG) or Lactobacillus acidophilus +Lactobacillus bifidum is associated with reduced risk of necrotising enterocolitis (NEC)≥Stage II in preterm neonates born at ≤32 weeks' gestation. We conducted a retrospective cohort study on the effect of probiotic supplementation in very low birth weight infants in our neonatal unit by comparing two periods: before and after supplementation. The incidence of NEC≥Stage II, late-onset sepsis and all-cause mortality was compared for an equal period 'before' (Period I) and 'after' (Period II) RPS with LGG or L. acidophillus+L. bifidum. Multivariate logistic regression analysis was conducted to adjust for relevant confounders. The study population was composed of 261 neonates (Period I v. II: 134 v. 127) with comparable gestation duration and birth weights. In
%K Lactobacillus
%K Lactobacillus acidophillus
%K Lactobacillus bifidum
%K rhamnosus GG
%K LGG Lactobacillus rhamnosus GG
%K NEC necrotising enterocolitis
%K VLBW very low birth weight
%K Late-onset sepsis
%K Necrotising enterocolitis
%K Probiotics
%K Very low birth weight infants
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