RT Journal Article T1 Functional rehabilitation of upper limb apraxia in poststroke patients: study protocol for a randomized controlled trial. A1 Pérez-Mármol, Jose Manuel A1 García-Ríos, M Carmen A1 Barrero-Hernandez, Francisco J A1 Molina-Torres, Guadalupe A1 Brown, Ted A1 Aguilar-Ferrándiz, María Encarnación K1 Apraxia K1 Stroke K1 Rehabilitation neurológica K1 Protocolos clínicos K1 Terapia combinada K1 Evaluación de la discapacidad K1 Método doble ciego K1 Lateralidad funcional K1 Actividad motora K1 Terapia ocupacional K1 Modalidades de fisioterapia K1 Recuperación de la función K1 España K1 Accidente cerebrovascular K1 Encuestas y Cuestionarios K1 Factores de tiempo K1 Actividades cotidianas K1 Resultado del tratamiento K1 Proyectos de investigación AB BACKGROUNDUpper limb apraxia is a common disorder associated with stroke that can reduce patients' independence levels in activities of daily living and increase levels of disability. Traditional rehabilitation programs designed to promote the recovery of upper limb function have mainly focused on restorative or compensatory approaches. However, no previous studies have been completed that evaluate a combined intervention method approach, where patients concurrently receive cognitive training and learn compensatory strategies for enhancing daily living activities.METHODS/DESIGNThis study will use a two-arm, assessor-blinded, parallel, randomized controlled trial design, involving 40 patients who present a left- or right-sided unilateral vascular lesion poststroke and a clinical diagnosis of upper limb apraxia. Participants will be randomized to either a combined functional rehabilitation or a traditional health education group. The experimental group will receive an 8-week combined functional program at home, including physical and occupational therapy focused on restorative and compensatory techniques for upper limb apraxia, 3 days per week in 30-min intervention periods. The control group will receive a conventional health education program once a month over 8 weeks, based on improving awareness of physical and functional limitations and facilitating the adaptation of patients to the home. Study outcomes will be assessed immediately postintervention and at the 2-month follow-up. The primary outcome measure will be basic activities of daily living skills as assessed with the Barthel Index. Secondary outcome measures will include the following: 1) the Lawton and Brody Instrumental Activities of Daily Living Scale, 2) the Observation and Scoring of ADL-Activities, 3) the De Renzi Test for Ideational Apraxia, 4) the De Renzi Test for Ideomotor Apraxia, 5) Recognition of Gestures, 6) the Test of Upper Limb Apraxia (TULIA), and 7) the Quality of Life Scale For Stroke (ECVI-38).DISCUSSIONThis trial is expected to clarify the effectiveness of a combined functional rehabilitation approach compared to a conservative intervention for improving upper limb movement and function in poststroke patients.TRIAL REGISTRATIONClinical Trial Gov number NCT02199093 . The protocol registration was received 23 July 2014. Participant enrollment began on 1 May 2014. The trial is expected to be completed in March 2016. PB BioMed Central YR 2015 FD 2015-11-05 LK http://hdl.handle.net/10668/2605 UL http://hdl.handle.net/10668/2605 LA en NO Pérez-Mármol JM, García-Ríos MC, Barrero-Hernandez FJ, Molina-Torres G, Brown T, Aguilar-Ferrándiz ME. Functional rehabilitation of upper limb apraxia in poststroke patients: study protocol for a randomized controlled trial. Trials. 2015; 16:508 NO Journal Article; Randomized Controlled Trial; DS RISalud RD Apr 10, 2025