TY  - JOUR
AU  - Rubio-Navarro, Alfonso
AU  - Sanchez-Niño, Maria Dolores
AU  - Guerrero-Hue, Melania
AU  - García-Caballero, Cristina
AU  - Gutiérrez, Eduardo
AU  - Yuste, Claudia
AU  - Sevillano, Ángel
AU  - Praga, Manuel
AU  - Egea, Javier
AU  - Román, Elena
AU  - Cannata, Pablo
AU  - Ortega, Rosa
AU  - Cortegano, Isabel
AU  - de Andrés, Belén
AU  - Gaspar, María Luisa
AU  - Cadenas, Susana
AU  - Ortiz, Alberto
AU  - Egido, Jesús
AU  - Moreno, Juan Antonio
PY  - 2018
DO  - 10.1002/path.5011
UR  - http://hdl.handle.net/10668/11874
T2  - The Journal of pathology
AB  - Recurrent and massive intravascular haemolysis induces proteinuria, glomerulosclerosis, and progressive impairment of renal function, suggesting podocyte injury. However, the effects of haemoglobin (Hb) on podocytes remain unexplored. Our results show...
LA  - en
KW  - Nrf2
KW  - apoptosis
KW  - haemoglobin
KW  - intravascular haemolysis
KW  - oxidative stress
KW  - podocyte
KW  - Acute Kidney Injury
KW  - Adult
KW  - Anemia, Hemolytic
KW  - Animals
KW  - Apoptosis
KW  - Cell Line
KW  - Disease Models, Animal
KW  - Endocytosis
KW  - Female
KW  - Ferritins
KW  - Heme Oxygenase-1
KW  - Hemoglobins
KW  - Hemolysis
KW  - Humans
KW  - Low Density Lipoprotein Receptor-Related Protein-2
KW  - Male
KW  - Membrane Proteins
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - NF-E2-Related Factor 1
KW  - NF-E2-Related Factor 2
KW  - Oxidative Stress
KW  - Phosphorylation
KW  - Podocytes
KW  - Receptors, Cell Surface
KW  - Young Adult
TI  - Podocytes are new cellular targets of haemoglobin-mediated renal damage.
TY  - research article
VL  - 244
ER  -