TY - JOUR AU - Gonzalez-Rincon, Julia AU - Garcia-Vela, Jose A. AU - Gomez, Sagrario AU - Fernandez-Cuevas, Belen AU - Nova-Gurumeta, Sara AU - Perez-Sanz, Nuria AU - Alcoceba, Miguel AU - Gonzalez, Marcos AU - Anguita, Eduardo AU - Lopez-Jimenez, Javier AU - Gonzalez-Barca, Eva AU - Yanez, Lucrecia AU - Perez-Persona, Ernesto AU - de la Serna, Javier AU - Fernandez-Zarzoso, Miguel AU - Deben, Guillermo AU - Penalver, Francisco J. AU - Fernandez, Maria C. AU - de Oteyza, Jaime Perez AU - Andreu, M. angeles AU - Ruiz-Guinaldo, M. angeles AU - Paz-Arias, Raquel AU - Garcia-Malo, M. Dolores AU - Recasens, Valle AU - Collado, Rosa AU - Cordoba, Raul AU - Navarro-Matilla, Belen AU - Sanchez-Beato, Margarita AU - Garcia-Marco, Jose A. PY - 2021 DO - 10.1371/journal.pone.0257353 SN - 1932-6203 UR - https://hdl.handle.net/10668/25213 T2 - Plos one AB - Chronic Lymphocytic Leukemia (CLL) is the most prevalent leukemia in Western countries and is notable for its variable clinical course. This variability is partly reflected by the mutational status of IGHV genes. Many CLL samples have been studied in... LA - en PB - Public library science KW - Recurrent mutations KW - Clinical impact KW - Coding genome KW - Cll KW - Fludarabine KW - Notch1 KW - Survival KW - Sf3b1 KW - Tp53 KW - Cyclophosphamide TI - Genomic mutation profile in progressive chronic lymphocytic leukemia patients prior to first-line chemoimmunotherapy with FCR and rituximab maintenance (REM) TY - research article VL - 16 ER -