TY - JOUR AU - Mok, Tony S AU - Cheng, Ying AU - Zhou, Xiangdong AU - Lee, Ki Hyeong AU - Nakagawa, Kazuhiko AU - Niho, Seiji AU - Chawla, Alka AU - Rosell, Rafael AU - Corral, Jesus AU - Migliorino, Maria Rita AU - Pluzanski, Adam AU - Noonan, Kay AU - Tang, Yiyun AU - Pastel, Malaika AU - Wilner, Keith D AU - Wu, Yi-Long PY - 2021 DO - 10.1007/s40265-020-01441-6 UR - http://hdl.handle.net/10668/16812 T2 - Drugs AB - ARCHER 1050, an ongoing, randomized, open-label, phase III trial of dacomitinib versus gefitinib in newly diagnosed patients with advanced non-small-cell lung cancer (NSCLC) and an EGFR-activating mutation, reported significant improvement in overall... LA - en KW - Aged KW - Antineoplastic Combined Chemotherapy Protocols KW - Carcinoma, Non-Small-Cell Lung KW - Dose-Response Relationship, Drug KW - ErbB Receptors KW - Female KW - Gefitinib KW - Humans KW - Lung Neoplasms KW - Male KW - Mutation KW - Protein Kinase Inhibitors KW - Quinazolinones KW - Survival Analysis TI - Updated Overall Survival in a Randomized Study Comparing Dacomitinib with Gefitinib as First-Line Treatment in Patients with Advanced Non-Small-Cell Lung Cancer and EGFR-Activating Mutations. TY - research article VL - 81 ER -