RT Journal Article
T1 Implementation of a computerized decision support system to improve the appropriateness of antibiotic therapy using local microbiologic data.
A1 Rodriguez-Maresca, Manuel
A1 Sorlozano, Antonio
A1 Grau, Magnolia
A1 Rodriguez-Castaño, Rocio
A1 Ruiz-Valverde, Andres
A1 Gutierrez-Fernandez, Jose
K1 Medicamentos por prescripción
K1 Antibacterianos
K1 Bacteria
K1 Infección hospitalaria
K1 Sistemas de apoyo a decisiones clínicas
K1 Farmacorresistencia bacteriana
K1 Implantación de planes de salud
K1 Directrices para la planificación en salud
K1 Humanos
K1 Duración de estancia hospitalaria
AB A prospective quasi-experimental study was undertaken in 218 patients with suspicion of nosocomial infection hospitalized in a polyvalent ICU where a new electronic device (GERB) has been designed for antibiotic prescriptions. Two GERB-based applications were developed to provide local resistance maps (LRMs) and preliminary microbiological reports with therapeutic recommendation (PMRTRs). Both applications used the data in the Laboratory Information System of the Microbiology Department to report on the optimal empiric therapeutic option, based on the most likely susceptibility profile of the microorganisms potentially responsible for infection in patients and taking into account the local epidemiology of the hospital department/unit. LRMs were used for antibiotic prescription in 20.2% of the patients and PMRTRs in 78.2%, and active antibiotics against the finally identified bacteria were prescribed in 80.0% of the former group and 82.4% of the latter. When neither LMRs nor PMRTRs were considered for empiric treatment prescription, only around 40% of the antibiotics prescribed were active. Hence, the percentage appropriateness of the empiric antibiotic treatments was significantly higher when LRM or PMRTR guidelines were followed rather than other criteria. LRMs and PMRTRs applications are dynamic, highly accessible, and readily interpreted instruments that contribute to the appropriateness of empiric antibiotic treatments.
PB Hindawi Publishing Corporation
YR 2014
FD 2014-08-17
LK http://hdl.handle.net/10668/2390
UL http://hdl.handle.net/10668/2390
LA en
NO Rodriguez-Maresca M, Sorlozano A, Grau M, Rodriguez-Castaño R, Ruiz-Valverde A, Gutierrez-Fernandez J. Implementation of a computerized decision support system to improve the appropriateness of antibiotic therapy using local microbiologic data. Biomed Res Int; 2014:395434
NO Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 8, 2025