TY - JOUR AU - Martínez-Muñoz, Laura AU - Rodríguez-Frade, José Miguel AU - Barroso, Rubén AU - Sorzano, Carlos Óscar S AU - Torreño-Pina, Juan A AU - Santiago, César A AU - Manzo, Carlo AU - Lucas, Pilar AU - García-Cuesta, Eva M AU - Gutierrez, Enric AU - Barrio, Laura AU - Vargas, Javier AU - Cascio, Graciela AU - Carrasco, Yolanda R AU - Sánchez-Madrid, Francisco AU - García-Parajo, María F AU - Mellado, Mario PY - 2018 DO - 10.1016/j.molcel.2018.02.034 UR - http://hdl.handle.net/10668/12317 T2 - Molecular cell AB - A current challenge in cell motility studies is to understand the molecular and physical mechanisms that govern chemokine receptor nanoscale organization at the cell membrane, and their influence on cell response. Using single-particle tracking and... LA - en KW - GPCR KW - TIRF KW - chemokine receptors KW - chemokines KW - live cell imaging KW - receptor clustering KW - receptor dynamics KW - single particle tracking KW - Actin Cytoskeleton KW - Amino Acid Motifs KW - Animals KW - CD4 Antigens KW - Cell Membrane KW - Cell Movement KW - Chemokine CXCL12 KW - HEK293 Cells KW - Humans KW - Jurkat Cells KW - Ligands KW - Mice, Inbred C57BL KW - Mutation KW - Nanoparticles KW - Protein Multimerization KW - Protein Transport KW - Receptors, CXCR4 KW - Signal Transduction KW - Single Molecule Imaging KW - T-Lymphocytes TI - Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function. TY - research article VL - 70 ER -