TY - JOUR AU - Garrido, P AU - Hladun, R AU - de Álava, E AU - Álvarez, R AU - Bautista, F AU - López-Ríos, F AU - Colomer, R AU - Rojo, F PY - 2021 DO - 10.1007/s12094-021-02558-0 UR - http://hdl.handle.net/10668/17220 T2 - Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico AB - The recent identification of rearrangements of neurotrophic tyrosine receptor kinase (NTRK) genes and the development of specific fusion protein inhibitors, such as larotrectinib and entrectinib, have revolutionised the diagnostic and clinical... LA - en KW - Gene fusions KW - Molecular oncology KW - Mutations KW - Neoplasm KW - Target therapies KW - Adult KW - Age Factors KW - Benzamides KW - Child KW - Consensus KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Immunohistochemistry KW - In Situ Hybridization, Fluorescence KW - Indazoles KW - Membrane Glycoproteins KW - Molecular Targeted Therapy KW - Neoplasms KW - Oncogene Proteins, Fusion KW - Protein Kinase Inhibitors KW - Pyrazoles KW - Pyrimidines KW - Receptor, trkA KW - Receptor, trkB KW - Receptor, trkC KW - Reverse Transcriptase Polymerase Chain Reaction KW - Societies, Medical KW - Spain TI - Multidisciplinary consensus on optimising the detection of NTRK gene alterations in tumours. TY - research article VL - 23 ER -