RT Journal Article
T1 Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study.
A1 Galmes-Panades, Aina M
A1 Varela-Mato, Veronica
A1 Konieczna, Jadwiga
A1 Wärnberg, Julia
A1 Martínez-González, Miguel Ángel
A1 Salas-Salvadó, Jordi
A1 Corella, Dolores
A1 Schröder, Helmut
A1 Vioque, Jesús
A1 Alonso-Gómez, Ángel M
A1 Martínez, J Alfredo
A1 Serra-Majem, Luís
A1 Estruch, Ramon
A1 Tinahones, Francisco J
A1 Lapetra, José
A1 Pintó, Xavier
A1 Tur, Josep A
A1 Garcia-Rios, Antonio
A1 Riquelme-Gallego, Blanca
A1 Gaforio, José Juan
A1 Matía-Martín, Pilar
A1 Daimiel, Lidia
A1 Micó Pérez, Rafael Manuel
A1 Vidal, Josep
A1 Vázquez, Clotilde
A1 Ros, Emilio
A1 Garcia-Arellano, Ana
A1 Díaz-López, Andrés
A1 Asensio, Eva M
A1 Castañer, Olga
A1 Fiol, Francisca
A1 Mira-Castejón, Luis Alfredo
A1 Moreno Rodríguez, Anai
A1 Benavente-Marín, Juan Carlos
A1 Abete, Itziar
A1 Tomaino, Laura
A1 Casas, Rosa
A1 Barón López, F Javier
A1 Fernández-García, José Carlos
A1 Santos-Lozano, José Manuel
A1 Galera, Ana
A1 Mascaró, Catalina M
A1 Razquin, Cristina
A1 Papandreou, Christopher
A1 Portoles, Olga
A1 Pérez-Vega, Karla Alejandra
A1 Fiol, Miguel
A1 Compañ-Gabucio, Laura
A1 Vaquero-Luna, Jessica
A1 Ruiz-Canela, Miguel
A1 Becerra-Tomás, Nerea
A1 Fitó, Montserrat
A1 Romaguera, Dora
K1 Cardiometabolic risk
K1 Inactive time
K1 Isotemporal substitution
K1 Light physical activity
K1 Moderate to vigorous physical activity
K1 Time in bed
AB This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating inactive time to time in bed, light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) on cardio-metabolic risk factors, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. This is a cross-sectional analysis of baseline data from 2189 Caucasian men and women (age 55-75 years, BMI 27-40 Kg/m2) from the PREDIMED-Plus study (http://www.predimedplus.com/). All participants had ≥3 components of the metabolic syndrome. Inactive time, physical activity and time in bed were objectively determined using triaxial accelerometers GENEActiv during 7 days (ActivInsights Ltd., Kimbolton, United Kingdom). Multiple adjusted linear and logistic regression models were used. Isotemporal substitution regression modelling was performed to assess the relationship of replacing the amount of time spent in one activity for another, on each outcome, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. Inactive time was associated with indicators of obesity and the metabolic syndrome. Reallocating 30 min per day of inactive time to 30 min per day of time in bed was associated with lower BMI, waist circumference and glycated hemoglobin (HbA1c) (all p-values  Inactive time was associated with a poor cardio-metabolic profile. Isotemporal substitution of inactive time with MVPA and LPA or time in bed could have beneficial impact on cardio-metabolic health. The trial was registered at the International Standard Randomized Controlled Trial (ISRCTN: http://www.isrctn.com/ISRCTN89898870) with number 89898870 and registration date of 24 July 2014, retrospectively registered.
YR 2019
FD 2019-12-23
LK http://hdl.handle.net/10668/14872
UL http://hdl.handle.net/10668/14872
LA en
DS RISalud
RD Apr 7, 2025