TY - JOUR AU - Macias, David AU - Cowburn, Andrew S AU - Torres-Torrelo, Hortensia AU - Ortega-Sáenz, Patricia AU - López-Barneo, José AU - Johnson, Randall S PY - 2018 DO - 10.7554/eLife.34681 UR - http://hdl.handle.net/10668/12370 T2 - eLife AB - Mammalian adaptation to oxygen flux occurs at many levels, from shifts in cellular metabolism to physiological adaptations facilitated by the sympathetic nervous system and carotid body (CB). Interactions between differing forms of adaptive response... LA - en KW - carotid body KW - computational biology KW - hypoxia KW - mouse KW - sympathetic nerves KW - systems biology KW - Animals KW - Basic Helix-Loop-Helix Transcription Factors KW - Carotid Body KW - Cell Differentiation KW - Mice TI - HIF-2α is essential for carotid body development and function. TY - research article VL - 7 ER -