TY  - JOUR
AU  - Flasch, Diane A
AU  - Macia, Ángela
AU  - Sánchez, Laura
AU  - Ljungman, Mats
AU  - Heras, Sara R
AU  - García-Pérez, José L
AU  - Wilson, Thomas E
AU  - Moran, John V
PY  - 2019
DO  - 10.1016/j.cell.2019.02.050
UR  - http://hdl.handle.net/10668/13796
T2  - Cell
AB  - L1 retrotransposon-derived sequences comprise approximately 17% of the human genome. Darwinian selective pressures alter L1 genomic distributions during evolution, confounding the ability to determine initial L1 integration preferences. Here, we...
LA  - en
KW  - DNA replication
KW  - Fanconi anemia
KW  - LINE-1
KW  - chromatin
KW  - evolution
KW  - human genome
KW  - integration
KW  - retrotransposon
KW  - transcription
KW  - transposable element
KW  - Cell Line
KW  - Endonucleases
KW  - Genome, Human
KW  - Genome-Wide Association Study
KW  - Genomics
KW  - HeLa Cells
KW  - Humans
KW  - Long Interspersed Nucleotide Elements
KW  - Mutagenesis, Insertional
KW  - Retroelements
TI  - Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication.
TY  - research article
VL  - 177
ER  -