RT Journal Article
T1 No association between fish consumption and risk of stroke in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain): a 13·8-year follow-up study.
A1 Amiano, Pilar
A1 Chamosa, Saioa
A1 Etxezarreta, Nerea
A1 Arriola, Larraitz
A1 Moreno-Iribas, Conchi
A1 Huerta, José-María
A1 Egües, Nerea
A1 Guevara, Marcela
A1 Navarro, Carmen
A1 Chirlaque, María-Dolores
A1 Sanchez-Perez, Maria-Jose
A1 Molina-Montes, Esther
A1 Requena, Mar
A1 Quirós, Jose-Ramón
A1 Obón-Santacana, Mireia
A1 Jakszyn, Paula
A1 González, Carlos-Alberto
A1 Dorronsoro, Miren
K1 Cohort studies
K1 Fish consumption
K1 Stroke
AB To prospectively assess the associations between lean fish, fatty fish and total fish intakes and risk of stroke in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain). Fish intake was estimated from a validated dietary questionnaire. Cox proportional hazards regression models were used to assess the association between the intakes of lean fish, fatty fish and total fish and stroke risk. Models were run separately for men and women. Five Spanish regions (Asturias, San Sebastian, Navarra, Granada and Murcia). Individuals (n 41 020; 15 490 men and 25 530 women) aged 20-69 years, recruited from 1992 to 1996 and followed-up until December 2008 (December 2006 in the case of Asturias). Only participants with definite incident stroke were considered as cases. During a mean follow-up of 13·8 years, 674 strokes were identified and subsequently validated by record linkage with hospital discharge databases, primary-care records and regional mortality registries, comprising 531 ischaemic, seventy-nine haemorrhagic, forty-two subarachnoid and twenty-two unspecific strokes. After multiple adjustments, no significant associations were observed between lean fish, fatty fish and total fish consumption and the risk of stroke in men or women. In men, results revealed a non-significant trend towards an inverse association between lean fish (hazard ratio=0·84; 95 % CI 0·55, 1·29, P trend=0·06) and total fish consumption (hazard ratio=0·77; 95 % CI 0·51, 1·16, P trend=0·06) and risk of total stroke. In the EPIC-Spain cohort, no association was found between lean fish, fatty fish and total fish consumption and risk of stroke.
YR 2016
FD 2016
LK http://hdl.handle.net/10668/9841
UL http://hdl.handle.net/10668/9841
LA en
DS RISalud
RD Apr 7, 2025