RT Journal Article
T1 Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition.
A1 Obón-Santacana, Mireia
A1 Luján-Barroso, Leila
A1 Freisling, Heinz
A1 Naudin, Sabine
A1 Boutron-Ruault, Marie-Christine
A1 Mancini, Francesca Romana
A1 Rebours, Vinciane
A1 Kühn, Tilman
A1 Katzke, Verena
A1 Boeing, Heiner
A1 Tjønneland, Anne
A1 Olsen, Anja
A1 Overvad, Kim
A1 Lasheras, Cristina
A1 Rodríguez-Barranco, Miguel
A1 Amiano, Pilar
A1 Santiuste, Carmen
A1 Ardanaz, Eva
A1 Khaw, Kay-Thee
A1 Wareham, Nicholas J
A1 Schmidt, Julie A
A1 Aune, Dagfinn
A1 Trichopoulou, Antonia
A1 Thriskos, Paschalis
A1 Peppa, Eleni
A1 Masala, Giovanna
A1 Grioni, Sara
A1 Tumino, Rosario
A1 Panico, Salvatore
A1 Bueno-de-Mesquita, Bas
A1 Sciannameo, Veronica
A1 Vermeulen, Roel
A1 Sonestedt, Emily
A1 Sund, Malin
A1 Weiderpass, Elisabete
A1 Skeie, Guri
A1 González, Carlos A
A1 Riboli, Elio
A1 Duell, Eric J
K1 EPIC
K1 diet
K1 intake
K1 nuts
K1 pancreatic cancer
K1 prospective cohort study
K1 seeds
AB Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estimate hazards ratio (HR) and 95% confidence intervals (95% CI) for nut intake and PDAC risk. Information on intake of nuts was obtained from the EPIC country-specific dietary questionnaires. After a mean follow-up of 14 years, 476,160 participants were eligible for the present study and included 1,283 PDAC cases. No association was observed between consumption of nuts and PDAC risk (highest intake vs nonconsumers: HR, 0.89; 95% CI, 0.72-1.10; p-trend = 0.70). Furthermore, no evidence for effect-measure modification was observed when different subgroups were analyzed. Overall, in EPIC, the highest intake of nuts was not statistically significantly associated with PDAC risk.
YR 2019
FD 2019-06-06
LK http://hdl.handle.net/10668/13989
UL http://hdl.handle.net/10668/13989
LA en
DS RISalud
RD Apr 9, 2025