TY - JOUR AU - Muñoz-Fernández, Raquel AU - De La Mata, Claudia AU - Requena, Francisco AU - Martín, Francisco AU - Fernandez-Rubio, Pablo AU - Llorca, Tatiana AU - Ruiz-Magaña, Maria José AU - Ruiz-Ruiz, Carmen AU - Olivares, Enrique G. PY - 2019 DO - 10.1186/s13287-019-1284-z UR - http://hdl.handle.net/10668/3150 T2 - Stem Cell Research & Therapy AB - Human decidual stromal cells (DSCs) are involved in the maintenance and development of pregnancy, in which they play a key role in the induction of immunological maternal-fetal tolerance. Precursors of DSCs (preDSCs) are located around the vessels,... LA - en PB - BioMed Central Ltd. KW - Clone cells KW - Decidua KW - Immune tolerance KW - Immunotherapy KW - Mesenchymal stromal cells KW - Predecidual stromal cells KW - Recurrent abortion KW - Células clonales KW - Tolerancia inmunológica KW - Inmunoterapia KW - Células madre mesenquimatosas KW - Aborto habitual KW - Medical Subject Headings::Diseases::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications::Abortion, Spontaneous::Abortion, Habitual KW - Medical Subject Headings::Diseases::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications::Abortion, Spontaneous KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured KW - Medical Subject Headings::Anatomy::Embryonic Structures::Placenta::Decidua KW - Medical Subject Headings::Diseases::Animal Diseases::Disease Models, Animal KW - Medical Subject Headings::Anatomy::Urogenital System::Genitalia::Genitalia, Female::Uterus::Endometrium KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Transplantation::Cell Transplantation::Stem Cell Transplantation::Mesenchymal Stem Cell Transplantation KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy TI - Human predecidual stromal cells are mesenchymal stromal/stem cells and have a therapeutic effect in an immune-based mouse model of recurrent spontaneous abortion TY - research article ER -