TY  - JOUR
AU  - López-Escobar, Beatriz
AU  - Fernández-Torres, Rut
AU  - Vargas-López, Viviana
AU  - Villar-Navarro, Mercedes
AU  - Rybkina, Tatyana
AU  - Rivas-Infante, Eloy
AU  - Hernández-Viñas, Ayleen
AU  - Álvarez Del Vayo, Concepción
AU  - Caro-Vega, José
AU  - Sánchez-Alcázar, José A.
AU  - González-Meneses, Antonio
AU  - Carrión, M. Ángel
AU  - Ybot-González, Patricia
PY  - 2020
DO  - 10.1038/s41598-020-64626-9
UR  - http://hdl.handle.net/10668/3717
T2  - Scientific Reports
AB  - The use of first and second generation antiepileptic drugs during pregnancy doubles the risk of major congenital malformations and other teratogenic defects. Lacosamide (LCM) is a third-generation antiepileptic drug that interacts with collapsing...
LA  - en
PB  - Springer Nature
KW  - Lacosamide
KW  - Animales
KW  - Mice
KW  - Fetus
KW  - Dose-response relationship, drug
KW  - Memory
KW  - Pregnancy
KW  - Schizophrenia
KW  - Malformations
KW  - Lacosamida
KW  - Animales
KW  - Ratones
KW  - Feto
KW  - Relación dosis-respuesta a droga
KW  - Memoria
KW  - Embarazo
KW  - Esquizofrenia
KW  - Anomalías congénitas
KW  - Efectos tardíos de la exposición prenatal
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Dose-Response Relationship, Drug
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Anatomy::Embryonic Structures::Fetus
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Incidence
KW  - Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Movement::Locomotion
KW  - Medical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Learning::Memory
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy
KW  - Medical Subject Headings::Diseases::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications::Prenatal Injuries::Prenatal Exposure Delayed Effects
KW  - Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Schizophrenia and Disorders with Psychotic Features::Schizophrenia
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Central Nervous System Agents::Anticonvulsants
TI  - Lacosamide intake during pregnancy increases the incidence of foetal malformations and symptoms associated with schizophrenia in the offspring of mice
TY  - research article
ER  -