RT Conference Proceedings
T1 INCREASED LIVER DISEASE RISK IN RHEUMATOID ARTHRITIS IS ASSOCIATED WITH DISEASE ACTIVITY, INFLAMMATORY MARKERS, INSULIN RESISTANCE AND ACPAS. INFLUENCE OF METHOTREXATE
A1 Arias De la Rosa, I.
A1 Ruiz-Ponce, M.
A1 Lopez, L. Cuesta
A1 Gahete, M. D.
A1 Herman-Sanchez, N.
A1 Lucendo-Villarin, A.
A1 Navarro-Sanchez, P.
A1 Abalos-Aguilera, M. C.
A1 Perez-Sanchez, C.
A1 Castro, R. Ortega
A1 Gutierrez, J. Calvo
A1 Lopez-Pedrera, C.
A1 Contreras, A. Escudero
A1 Estevez, E. Collantes
A1 Puerto, N. Barbarroja
K1 Humans
K1 Methotrexate
K1 Non-alcoholic Fatty Liver Disease
K1 Autoimmunity
AB Background: Liver alterations, especially nonalcoholic fatty liver disease(NAFLD) are associated with Rheumatoid Arthritis (RA). This abnormalityappears as asymptomatic and can progress to a severe liver damage rapidly.Chronic inflammation, treatment with methotrexate (MTX) or even autoimmunity are factors that might be involved, however the mechanisms related to this comorbidity in RA are not completely stablished yet.Objectives: 1) To evaluate the liver disease risk in RA patients through feasible indexes to be used in the daily clinical practice and its relationship with clinical features of the disease; 2) To analyze the impact of antibodies to citrullinated proteins antigens (ACPAs) on hepatic function; 3) To examine the influence ofMTX treatment on classical parameters and new indexes of hepatic dysfunction in a cross-sectional and longitudinal cohort.
PB BMJ Group
SN 0003-4967
YR 2022
FD 2022-06-01
LK http://hdl.handle.net/10668/20107
UL http://hdl.handle.net/10668/20107
LA en
NO De la Rosa IA, Ruiz-Ponce M, López LC, Gahete MD, Herman-Sanchez N, Lucendo-Villarin A, et al. AB0084 INCREASED LIVER DISEASE RISK IN RHEUMATOID ARTHRITIS IS ASSOCIATED WITH DISEASE ACTIVITY, INFLAMMATORY MARKERS, INSULIN RESISTANCE AND ACPAS. INFLUENCE OF METHOTREXATE. Annals Of The Rheumatic Diseases [Internet]. 23 de mayo de 2022;81(Suppl 1):1173.3-1174.
DS RISalud
RD Apr 18, 2025