TY  - JOUR
AU  - Ishikawa, Masaaki
AU  - Garcia-Mateo, Nadia
AU  - Čusak, Alen
AU  - Lopez-Hernandez, Iris
AU  - Fernandez-Martinez, Marta
AU  - Müller, Marcus
AU  - Rüttiger, Lukas
AU  - Singer, Wibke
AU  - Löwenheim, Hubert
AU  - Kosec, Gregor
AU  - Fujs, Štefan
AU  - Martinez-Martinez, Luis
AU  - Schimmang, Thomas
AU  - Petković, Hrvoje
AU  - Knipper, Marlies
AU  - Duran-Alonso, M Beatriz
PY  - 2018
DO  - 10.1038/s41598-019-38634-3
UR  - http://hdl.handle.net/10668/13601
T2  - Scientific reports
AB  - Spread of antimicrobial resistance and shortage of novel antibiotics have led to an urgent need for new antibacterials. Although aminoglycoside antibiotics (AGs) are very potent anti-infectives, their use is largely restricted due to serious...
LA  - en
PB  - Nature Publishing Group
KW  - Hearing Loss
KW  - Nebramycin
KW  - Neomycin
KW  - Ototoxicity
KW  - Protein Synthesis Inhibitors
KW  - Round Window, Ear
KW  - Aminoglycosides
KW  - Animals
KW  - Anti-Bacterial Agents
KW  - Anti-Infective Agents
KW  - Cell Line
KW  - Drug Resistance, Bacterial
KW  - Gentamicins
KW  - Guinea Pigs
KW  - Hair Cells, Auditory, Inner
TI  - Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use.
TY  - research article
VL  - 9
ER  -